IngredientID 30752

Protease

C15H27N5O5

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Relationship Network

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Herb: 12Ingredient: 1Meta-analysis: 12Target: 12Links: 36
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Record Fields

Scalar fields from the final ingredient record.

Ingredient Id
30752
Core Entity Id
37362
Source Entity Count
1
Preferred Name
Protease
Name En
Pubchem Id
123985
Smiles Canonical
CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
Molecular Formula
C15H27N5O5
Molecular Weight
357.4110
Inchikey
LTLYEAJONXGNFG-DCAQKATOSA-N
Inchi
InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10-,11-/m0/s1
Isomeric Smiles
CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O
Cas Id
Ob Score
Mol Logp
-1.4609
Num H Donors
5
Num H Acceptors
5
Num Rotatable Bonds
11
Drug Likeness
0.1300
Polar Surface Area
Molecular Volume
Alogp

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Protease
Role
Molecule_name
Source
SymMap_v2
Preferred
Yes
Name
Protease
Role
preferred
Source
itcmdb_public
Preferred
Yes
Name
Protease
Role
preferred
Source
SymMap_v2
Preferred
Yes
Name
Protease
Role
preferred
Source
HERB_v2
Preferred
Yes
Name
protease
Role
preferred
Source
TCMBank
Preferred
Yes
Name
(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid
Role
alias
Source
HERB_v2
Preferred
No
Name
(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid
Role
alias
Source
itcmdb_public
Preferred
No
Name
(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Role
alias
Source
itcmdb_public
Preferred
No
Name
(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Role
alias
Source
HERB_v2
Preferred
No
Name
66701-25-5
Role
alias
Source
itcmdb_public
Preferred
No
Name
66701-25-5
Role
alias
Source
HERB_v2
Preferred
No
Name
CHEBI:30270
Role
alias
Source
itcmdb_public
Preferred
No
Name
CHEBI:30270
Role
alias
Source
HERB_v2
Preferred
No
Name
CHEMBL374508
Role
alias
Source
HERB_v2
Preferred
No
Name
CHEMBL374508
Role
alias
Source
itcmdb_public
Preferred
No
Name
Proteinase inhibitor E 64
Role
alias
Source
itcmdb_public
Preferred
No
Name
Proteinase inhibitor E 64
Role
alias
Source
HERB_v2
Preferred
No
Name
R76F7856MV
Role
alias
Source
HERB_v2
Preferred
No
Name
R76F7856MV
Role
alias
Source
itcmdb_public
Preferred
No
Name
e-64
Role
alias
Source
HERB_v2
Preferred
No
Name
e-64
Role
alias
Source
itcmdb_public
Preferred
No

Aliases

Additional names normalized into the restored final schema.

(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid66701-25-5CHEBI:30270CHEMBL374508Proteinase inhibitor E 64R76F7856MVe-64

Cross References

Trusted external identifiers retained for this final record.

Herb
HBIN040895
Npass
NPC483965
Tcmid
24226
Sym Map
SMIT18555
Pub Chem
123985
Tcmbank
TCMBANKIN024826

Attributes

Merged source attributes and domain-specific metadata.

Type
Other ingredients
In Ch I
InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10-,11-/m0/s1
Mol Wt
357.4110000000001
Smiles
CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
Mol Log P
-1.460899999999994
Version
v1,v2
In Ch Ikey
LTLYEAJONXGNFG-DCAQKATOSA-N
Suppress
0
Num Hdonors
5
Drug Likeness
0.13
Num Hacceptors
5
Isomeric Smiles
CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O
Canonical Smiles
CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
Herb Alias Names
e-6466701-25-5Proteinase inhibitor E 64(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acidCHEMBL374508E 64CHEBI:30270E64R76F7856MV(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Molecular Formula
C15H27N5O5
Num Rotatable Bonds
11