DiseaseID 4454
髓系白血病
disease
Chronic myeloid leukaemia (CML) is the most common myeloproliferative disorder accounting for 15-20% of all leukaemia cases.
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Disease: 1Experiment: 4Formula: 15Herb: 12Symptom: 12Target: 24Links: 67
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 4454
- Core Entity Id
- 60804
- Source Entity Count
- 1
- Preferred Name
- Myeloid Leukemia
- Name Cn
- 髓系白血病
- Name Pinyin
- Sui Xi Bai Xue Bing
- Name En
- Myeloid Leukemia
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Hemic and Lymphatic DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic DiseasesSkin and Connective Tissue Diseases
- Do Class
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Abnormality of the immune system; Abnormality of blood and blood-forming tissues; Neoplasm
- Mesh Class Name
- Hemic and Lymphatic DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic DiseasesSkin and Connective Tissue Diseases
- Hpo Class Name
- Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
- Do Class Name
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Disease Definition
- Chronic myeloid leukaemia (CML) is the most common myeloproliferative disorder accounting for 15-20% of all leukaemia cases.
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Myeloid Leukemia
Role
preferred
Name
Disseminated Eosinophilic Collagen Disease
Role
preferred
Name
Hypereosinophilic Syndrome
Role
preferred
Name
Juvenile Myelomonocytic Leukemia
Role
preferred
Name
Leukemia, Chronic Myeloid
Role
preferred
Name
Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative
Role
preferred
Name
Leukemia, Myelomonocytic, Chronic
Role
preferred
Name
Chronic Myeloid Leukemia
Role
preferred
Name
Chronic Myelomonocytic Leukemia-1
Role
preferred
Name
Chronic Myelomonocytic Leukemia-2
Role
preferred
Name
Eosinophilic Leukemia
Role
preferred
Name
Idiopathic Hypereosinophilic Syndrome
Role
preferred
Name
Leukemia, Monocytic, Chronic
Role
preferred
Name
Loeffler'S Endocarditis
Role
preferred
Name
Monocytic Leukemia
Role
preferred
Name
Myeloid Leukemia, Chronic
Role
preferred
Name
Myelomonocytic Leukemia
Role
preferred
Name
ACML
Role
alias
Name
Atypical Chronic Myeloid Leukemia
Role
alias
Name
CML
Role
alias
Name
CMML
Role
alias
Name
Chronic Monocytic Leukaemia
Role
alias
Name
Chronic Monocytic Leukemia
Role
alias
Name
Chronic Myelocytic Leukemia
Role
alias
Name
Chronic Myelogenous Leukemia
Role
alias
Name
Chronic Myeloid Leukaemia
Role
alias
Name
Chronic Myelomonocytic Leukemia
Role
alias
Name
Hypereosinophilic Syndrome, Idiopathic
Role
alias
Name
JMML
Role
alias
Name
LEUKEMIA, CHRONIC MYELOGENOUS
Role
alias
Name
LEUKEMIA, CHRONIC MYELOID, ATYPICAL
Role
alias
Name
LEUKEMIA, CHRONIC MYELOMONOCYTIC
Role
alias
Name
LEUKEMIA, JUVENILE MYELOMONOCYTIC
Role
alias
Name
Leukemia, Eosinophilic
Role
alias
Name
Leukemia, Myelogenous, Chronic, Bcr-Abl Positive
Role
alias
Name
Leukemia, Myeloid
Role
alias
Name
Leukemia, Myelomonocytic, Juvenile
Role
alias
Name
Monocytic Leukaemia
Role
alias
Name
Monocytic Leukaemia, Unspecified
Role
alias
Name
Myeloid Leukaemia
Role
alias
Name
Myeloid Leukaemia, Unspecified
Role
alias
Name
Subacute Myeloid Leukaemia
Role
alias
Name
Subacute Myeloid Leukemia
Role
alias
Name
Syndrome, Hypereosinophilic
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0005506HP:0012209HP:0012324HP:0012325
Herb
HBDIS001709HBDIS001711HBDIS001713HBDIS001716HBDIS002024HBDIS004338HBDIS004339HBDIS004340HBDIS005612HBDIS008508HBDIS010452HBDIS013286HBDIS013680HBDIS013681HBDIS014534
Me Sh
D007951D015464D015477D017681D054429D054438
Omim
607685607785608232
Umls
C0023470C0023473C0023480C0263662C0349639C1292772C1333043C1540912
Icd10
C92C92.1C92.2C92.20C92.9C92.90C93C93.1C93.10C93.9
Med Dra
10009013
Sym Map
SMDE01782SMDE04230SMDE04374SMDE07204SMDE07993SMDE09610SMDE10399SMDE10401SMDE11213
Do Class
DOID:14566DOID:7
Dis Ge Net
C0023466C0023470C0023473C0023480C0027019C0206141C0206142C0206143C0263662C0349639C0598894C1292772C1333043C1333044C1540912
Orphanet
521
Umls Sty
T047T191
Hpo Class
HP:0001871HP:0002664HP:0002715
Me Sh Class
C04C15C17
Etcm Disease
Juvenile Myelomonocytic LeukemiaLeukemia, Chronic Myeloid
Tcmbank Disease
1329216264167781915021438215392240227072658727465284138646795718282969939
Itcmdb Generated
ITX-DISEASE-014203510454ITX-DISEASE-66A1037FDB3DITX-DISEASE-67B70235EAEEITX-DISEASE-757D583863AFITX-DISEASE-AC7C27D730C4ITX-DISEASE-C31D403CEEBBITX-DISEASE-E300F25FB2E9
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v1,v2v2
Suppress
0
Page Title
Disease Juvenile Myelomonocytic Leukemia Details pageDisease Leukemia, Chronic Myeloid Details page
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Abnormality of the immune system; Abnormality of blood and blood-forming tissues; Neoplasm
Umls Disease Type
Disease or SyndromeNeoplastic Process
Basic Information
Disease Name
Juvenile Myelomonocytic Leukemia
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Blood diseases;Bone diseases;Immune diseases
Disease Name
Leukemia, Chronic Myeloid
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Blood diseases;Immune diseases
Disease Definition
Chronic myeloid leukaemia (CML) is the most common myeloproliferative disorder accounting for 15-20% of all leukaemia cases.NCI2016_02D:A chronic myelomonocytic leukemia characterized by the presence of less than 10 percent blasts in the bone marrow and less than 5 percent blasts in the peripheral blood.NCI2016_02D:A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene. (WHO, 2001)|MSH2017_2016_08_12:A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to CHRONIC MYELOID LEUKEMIA, but cytogenetically lacking a PHILADELPHIA CHROMOSOME or bcr/abl fusion gene (GENES, ABL).NCI2016_02D:A syndrome characterized by persistent eosinophilia, for which no underlying cause can be found, and which is associated with signs of organ involvement and dysfunction. This term has often been applied to cases of chronic eosinophilic leukemia. (WHO, 2001)|MSH2017_2016_08_12:A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.NCI2016_CDISC_1602D:A progressive, proliferative disease of blood cells, originating from immature granulocytes.|NCI2016_02D:A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia. When the proliferating myeloid cells are neutrophils, it is called chronic myelogenous leukemia.|MSH2017_2016_08_12:Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.|HPO2016_07_04:A leukemia that originates from a myeloid cell, that is the blood forming cells of the bone marrow. [HPO:probinson]|CSP2006:leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites.NCI2016_NCI-GLOSS_1602D:A rare form of childhood leukemia in which cancer cells often spread into tissues such as the skin, lung, and intestines.|NCI2016_02D:A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages. Myelomonocytic proliferation is seen in the bone marrow and the blood. The leukemic cells may infiltrate any tissue, however liver, spleen, lymph nodes, skin, and respiratory tract are the most common sites of involvement. (WHO, 2001)|MSH2017_2016_08_12:A leukemia affecting young children characterized by SPLENOMEGALY, enlarged lymph nodes, rashes, and hemorrhages. Traditionally classed as a myeloproliferative disease, it is now considered a mixed myeloproliferative-mylelodysplastic disorder.|HPO2016_07_04:Juvenile myelomonocytic leukemia (JMML) is a lethal myeloproliferative disease of young childhood characterized clinically by overproduction of myelomonocytic cells and by the in vitro phenotype of hematopoietic progenitor hypersensitivity to granulocyte-macrophage colony-stimulating factor. [HPO:probinson, pmid:18954903]NCI2016_NCI-GLOSS_1602D:A slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone marrow, crowding out other normal blood cells, such as other white blood cells, red blood cells, and platelets.|NCI2016_02D:A myelodysplastic/myeloproliferative neoplasm which is characterized by persistent monocytosis, absence of a Philadelphia chromosome and BCR/ABL fusion gene, fewer than 20 percent blasts in the bone marrow and blood, myelodysplasia, and absence of PDGFRA or PDGFRB rearrangement.|MSH2017_2016_08_12:A myelodysplastic-myeloproliferative disease characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood.|HPO2016_07_04:A myelodysplastic-myeloproliferative disease characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood. [HPO:probinson, MeSH:D015477]
Me Sh Disease Class
Hemic and Lymphatic DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic DiseasesSkin and Connective Tissue Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Hemic and Lymphatic DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic DiseasesSkin and Connective Tissue Diseases
Umls Semantic Type Name
Disease or SyndromeNeoplastic Process