DiseaseID 4292
甲状腺毒症
disease
NCI2016_NICHD_1602D:A syndrome caused by excessive levels of thyroid hormone due to overproduction or excessive release of stored thyroid hormone.|NCI2016_02D:A hypermetabolic syndrome caused by the elevation of thyroid
Relationship Network
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Disease: 1Formula: 5Herb: 7Symptom: 12Target: 24Links: 48
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 4292
- Core Entity Id
- 60619
- Source Entity Count
- 1
- Preferred Name
- Thyrotoxicosis
- Name Cn
- 甲状腺毒症
- Name Pinyin
- Jia Zhuang Xian Du Zheng
- Name En
- Thyrotoxicosis
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Endocrine System DiseasesEye Diseases; Immune System Diseases; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
- Do Class
- disease of anatomical entity
- Hpo Class
- Abnormality of the endocrine system
- Mesh Class Name
- Endocrine System DiseasesEye Diseases; Immune System Diseases; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
- Hpo Class Name
- Abnormality of the endocrine system
- Do Class Name
- disease of anatomical entity
- Disease Definition
- NCI2016_NICHD_1602D:A syndrome caused by excessive levels of thyroid hormone due to overproduction or excessive release of stored thyroid hormone.|NCI2016_02D:A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.|MSH2017_2016_08_12:A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
- Version
- v1,v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Thyrotoxicosis
Role
preferred
Name
Graves Disease
Role
preferred
Name
Hyperthyroidism
Role
preferred
Name
GRAVES DISEASE, SUSCEPTIBILITY TO, 1
Role
preferred
Name
Graves' Disease
Role
preferred
Name
Hyperthyroidism, Familial Gestational
Role
preferred
Name
Hyperthyroidism, Nonautoimmune
Role
preferred
Name
Primary Hyperthyroidism
Role
preferred
Name
Toxic Diffuse Goiter
Role
preferred
Name
Hyperthyroidism, Autoimmune
Role
alias
Name
Morbus Basedow
Role
alias
Name
Overactive Thyroid
Role
alias
Name
Thyrotoxicosis With Diffuse Goiter
Role
alias
Name
Thyrotoxicosis With Diffuse Goitre
Role
alias
Name
Thyrotoxicosis, Unspecified
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0000836HP:0011784HP:0100647
Herb
HBDIS001225HBDIS001470HBDIS002950HBDIS007935HBDIS015472HBDIS016513HBDIS018068HBDIS022099
Me Sh
D006111D006980D013971
Omim
603373609152
Umls
C0018213C0020550C0040156C1836706
Icd10
E05.0E05.9
Sym Map
SMDE03586SMDE05112SMDE09150SMDE09664SMDE13900
Do Class
DOID:7
Dis Ge Net
C0018213C0020550C0040156C0342122C1836706C1848795C1863959C3714618
Umls Sty
T033T047
Hpo Class
HP:0000818
Me Sh Class
C11C13C19C20
Etcm Disease
Hyperthyroidism, Familial GestationalHyperthyroidism, Nonautoimmune
Tcmbank Disease
16091182451868019021191212363426384322683689564
Itcmdb Generated
ITX-DISEASE-AF7CE58A83BDITX-DISEASE-DCBF5F5FA9F3ITX-DISEASE-E0E88B3416FAITX-DISEASE-E267EAE373EC
Attributes
Merged source attributes and domain-specific metadata.
Version
v1,v2v2
Suppress
01
Page Title
Disease Hyperthyroidism, Familial Gestational Details pageDisease Hyperthyroidism, Nonautoimmune Details page
Do Class Name
disease of anatomical entity
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of the endocrine system
Link Disease Id
2046.0
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of the endocrine system
Umls Disease Type
Disease or SyndromeFinding
Basic Information
Disease Name
Hyperthyroidism, Familial Gestational
Global Category
Genetic diseases;Rare diseases
Anatomical Category
Endocrine diseases;Reproductive diseases
Disease Name
Hyperthyroidism, Nonautoimmune
Global Category
Genetic diseases;Rare diseases
Anatomical Category
Cardiovascular diseases;Endocrine diseases;Immune diseases;Nephrological diseases
Disease Definition
NCI2016_NICHD_1602D:A syndrome caused by excessive levels of thyroid hormone due to overproduction or excessive release of stored thyroid hormone.|NCI2016_02D:A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.|MSH2017_2016_08_12:A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.NCI2016_NICHD_1602D:An autoimmune disorder characterized by excessive immunoglobulin stimulation of the thyroid gland resulting in hyperthyroidism.|NCI2016_02D:Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones.|MSH2017_2016_08_12:A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).|HPO2016_07_04:An autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones (a serious metabolic imbalance known as hyperthyroidism and thyrotoxicosis). This is caused by autoantibodies to the TSH-receptor (TSHR-Ab) that activate that TSH-receptor (TSHR), thereby stimulating thyroid hormone synthesis and secretion, and thyroid growth (causing a diffusely enlarged goiter). The resulting state of hyperthyroidism can cause a dramatic constellation of neuropsychological and physical signs and symptoms, which can severely compromise the patients. [HPO:sdoelken]|CSP2006:exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs.|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland|CHV2011_02:a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid glandNCI2016_NICHD_1602D:Overproduction of thyroid hormone.|NCI2016_NCI-GLOSS_1602D:Too much thyroid hormone. Symptoms include weight loss, chest pain, cramps, diarrhea, and nervousness.|NCI2016_CTCAE_1602D:A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose.|NCI2016_02D:Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.|MSH2017_2016_08_12:Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.|MEDLINEPLUS_20151021:<p>Your <a href='https://www.nlm.nih.gov/medlineplus/thyroiddiseases.html'>thyroid</a> is a butterfly-shaped gland in your neck, just above your collarbone. It is one of your endocrine glands, which make hormones. Thyroid hormones control the rate of many activities in your body. These include how fast you burn calories and how fast your heart beats. All of these activities are your body's metabolism. If your thyroid is too active, it makes more thyroid hormones than your body needs. This is called hyperthyroidism.</p> <p>Hyperthyroidism is more common in women, people with other thyroid problems, and those over 60 years old. Grave's disease, an autoimmune disorder, is the most common cause. Other causes include thyroid nodules, thyroiditis, consuming too much iodine, and taking too much synthetic thyroid hormone.</p> <p>The symptoms can vary from person to person. They may include</p> <ul> <li>Being nervous or irritable</li> <li>Mood swings</li> <li>Fatigue or muscle weakness</li> <li>Heat intolerance</li> <li>Trouble sleeping</li> <li>Hand tremors</li> <li>Rapid and irregular heartbeat</li> <li>Frequent bowel movements or diarrhea</li> <li>Weight loss</li> <li>Goiter, which is an enlarged thyroid that may cause the neck to look swollen</li> </ul> <p>To diagnose hyperthyroidism, your doctor will look at your symptoms, blood tests, and sometimes a thyroid scan. Treatment is with medicines, radioiodine therapy, or thyroid surgery. No single treatment works for everyone.</p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:An abnormality of thyroid physiology characterized by excessive secretion of the thyroid hormones thyroxine (i.e., T4) and/or 3,3',5-triiodo-L-thyronine zwitterion (i.e., triiodothyronine or T3). [HPO:probinson]|CSP2006:excessive functional activity of the thyroid gland.
Me Sh Disease Class
Endocrine System DiseasesEye Diseases; Immune System Diseases; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Endocrine System DiseasesEye Diseases; Immune System Diseases; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Umls Semantic Type Name
Disease or SyndromeFinding