DiseaseID 3799
糖尿病
disease
DEND syndrome is a very rare, generally severe form of neonatal diabetes mellitus (NDM, see this term) characterized by a triad of developmental delay, epilepsy, and neonatal diabetes.
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Disease: 1Experiment: 12Formula: 21Herb: 12Symptom: 12Target: 24Links: 82
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3799
- Core Entity Id
- 60049
- Source Entity Count
- 2
- Preferred Name
- Diabetes
- Name Cn
- 糖尿病
- Name Pinyin
- Tang Niao Bing
- Name En
- Diabetes
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System DiseasesEndocrine System DiseasesEndocrine System Diseases; Nervous System Diseases; Nutritional and Metabolic Diseases; Pathological Conditions, Signs and SymptomsFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; NeoplasmsNeoplasmsNeoplasms; Endocrine System DiseasesNervous System DiseasesNutritional and Metabolic DiseasesNutritional and Metabolic Diseases; Endocrine System DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases; Behavior and Behavior Mechanisms; Endocrine System Diseases
- Do Class
- disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferationdisease of metabolismgenetic disease; disease of metabolism
- Hpo Class
- Abnormality of metabolism/homeostasisAbnormality of metabolism/homeostasis; Abnormality of the endocrine systemNeoplasm; Abnormality of the endocrine systemNeoplasm; Abnormality of the genitourinary system
- Mesh Class Name
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System DiseasesEndocrine System DiseasesNeoplasmsNeoplasms; Endocrine System DiseasesNeoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital DiseasesNervous System DiseasesNutritional and Metabolic DiseasesNutritional and Metabolic Diseases; Endocrine System DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases; Behavior and Behavior MechanismsPathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
- Hpo Class Name
- Abnormality of metabolism/homeostasisAbnormality of metabolism/homeostasis; Abnormality of the endocrine systemAbnormality of the endocrine system; NeoplasmAbnormality of the genitourinary system; Neoplasm
- Do Class Name
- disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferationdisease of metabolismdisease of metabolism; genetic disease
- Disease Definition
- DEND syndrome is a very rare, generally severe form of neonatal diabetes mellitus (NDM, see this term) characterized by a triad of developmental delay, epilepsy, and neonatal diabetes.
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Diabetes
Role
preferred
Name
Chromophobe Renal Cell Carcinoma
Role
preferred
Name
Collecting Duct Carcinoma Of The Kidney
Role
preferred
Name
Conventional (Clear Cell) Renal Cell Carcinoma
Role
preferred
Name
Dend Syndrome
Role
preferred
Name
Diabetes Mellitus, Noninsulin-Dependent
Role
preferred
Name
Diabetes Mellitus, Permanent Neonatal
Role
preferred
Name
Diabetes Mellitus, Permanent Neonatal, With Neurologic Features
Role
preferred
Name
Insulin Resistance
Role
preferred
Name
Intraductal Papillary Adenocarcinoma With Invasion
Role
preferred
Name
Papillary Adenocarcinoma
Role
preferred
Name
Papillary Renal Cell Carcinoma
Role
preferred
Name
Papillary Renal Cell Carcinoma, Sporadic
Role
preferred
Name
Permanent Neonatal Diabetes Mellitus
Role
preferred
Name
Renal Cell Carcinoma
Role
preferred
Name
Renal Cell Carcinoma, Nonpapillary
Role
preferred
Name
Sarcomatoid Renal Cell Carcinoma
Role
preferred
Name
Thyroid Cancer, Nonmedullary, 1
Role
preferred
Name
Thyroid Neoplasm
Role
preferred
Name
DIABETES MELLITUS, NONINSULIN-DEPENDENT, 1 (disorder)
Role
preferred
Name
DIABETES MELLITUS, NONINSULIN-DEPENDENT, 2 (disorder)
Role
preferred
Name
DIABETES MELLITUS, TRANSIENT NEONATAL, 2 (disorder)
Role
preferred
Name
DIABETES MELLITUS, TRANSIENT NEONATAL, 3 (disorder)
Role
preferred
Name
Developmental Delay, Epilepsy, And Neonatal Diabetes
Role
preferred
Name
Diabetes Mellitus Autosomal Dominant Type Ii (Disorder)
Role
preferred
Name
Diabetes Mellitus, Non-Insulin-Dependent
Role
preferred
Name
Diabetes Mellitus, Transient Neonatal, 1
Role
preferred
Name
Familial Non-Medullary Thyroid Cancer
Role
preferred
Name
Familial Papillary Or Follicular Thyroid Carcinoma
Role
preferred
Name
INSULIN RESISTANCE, SUSCEPTIBILITY TO
Role
preferred
Name
Insulin Sensitivity
Role
preferred
Name
Insulin-Resistant Diabetes Mellitus
Role
preferred
Name
Malignant Neoplasm of Thyroid
Role
preferred
Name
NONPAPILLARY RENAL CARCINOMA 1 LOCUS
Role
preferred
Name
Neonatal Diabetes Mellitus
Role
preferred
Name
Nonmedullary Thyroid Carcinoma
Role
preferred
Name
Nonmedullary Thyroid Carcinoma, With Or Without Cell Oxyphilia
Role
preferred
Name
Papillary Renal Cell Carcinoma, Familial
Role
preferred
Name
Papillary Thyroid Carcinoma
Role
preferred
Name
Papillary Thyroid Microcarcinoma
Role
preferred
Name
Renal Medullary Carcinoma
Role
preferred
Name
THYROID CANCER, NONMEDULLARY, 4
Role
preferred
Name
THYROID CANCER, NONMEDULLARY, 5
Role
preferred
Name
Thyroid Carcinoma
Role
preferred
Name
Thyroid Gland Follicular Adenoma
Role
preferred
Name
Type 1 Papillary Renal Cell Carcinoma
Role
preferred
Name
ADENOCARCINOMA OF KIDNEY
Role
alias
Name
Adenocarcinoma, Papillary
Role
alias
Name
Carcinoma, Hypernephroid
Role
alias
Name
Carcinoma, Papillary Thyroid
Role
alias
Name
Carcinoma, Renal Cell
Role
alias
Name
Carcinoma, Thyroid
Role
alias
Name
Clear Cell Renal Cell Carcinoma
Role
alias
Name
Collecting Duct Carcinoma
Role
alias
Name
DEND
Role
alias
Name
DIABETES MELLITUS, PERMANENT, OF INFANCY
Role
alias
Name
DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST
Role
alias
Name
DIABETES MELLITUS, TYPE II
Role
alias
Name
Developmental Delay-epilepsy-neonatal Diabetes Syndrome
Role
alias
Name
Diabetes Mellitus Type 2
Role
alias
Name
Diabetes Mellitus Type Ii
Role
alias
Name
Diabetes Mellitus, Noninsulin-Dependent, 1
Role
alias
Name
Diabetes Mellitus, Noninsulin-Dependent, 2
Role
alias
Name
Diabetes Mellitus, Transient Neonatal, 2
Role
alias
Name
Diabetes Mellitus, Transient Neonatal, 3
Role
alias
Name
Diabetes Mellitus, Type 2
Role
alias
Name
Diabetes Mellitus, Type Ii, Autosomal Dominant
Role
alias
Name
FAMILIAL NONMEDULLARY THYROID CANCER, PAPILLARY
Role
alias
Name
Familial Nonmedullary Thyroid Cancer
Role
alias
Name
HYPERNEPHROMA
Role
alias
Name
Insulin Resistant Diabetes Mellitus
Role
alias
Name
Insulin-Resistant Diabetes
Role
alias
Name
MATURITY-ONSET DIABETES
Role
alias
Name
Malignant Neoplasm of Thyroid Gland
Role
alias
Name
Maturity-Onset Diabetes of The Young Type 2
Role
alias
Name
Maturity-Onset Diabetes of The Young, Type 2
Role
alias
Name
Monogenic Diabetes Of Infancy
Role
alias
Name
NIDDM
Role
alias
Name
NMTC1
Role
alias
Name
NONINSULIN-DEPENDENT DIABETES MELLITUS
Role
alias
Name
NONMEDULLARY THYROID CARCINOMA, PAPILLARY
Role
alias
Name
NRC1
Role
alias
Name
Neoplasia of The Thyroid Gland
Role
alias
Name
Neoplasm of The Thyroid Gland
Role
alias
Name
Niddm Diabetes Mellitus
Role
alias
Name
Non-Insulin Dependent Diabetes
Role
alias
Name
Noninsulin Dependent Diabetes Mellitus
Role
alias
Name
Noninsulin-Dependent Diabetes
Role
alias
Name
Noninsulin-Dependent Diabetes Mellitus 1
Role
alias
Name
Noninsulin-Dependent Diabetes Mellitus 2
Role
alias
Name
Nonpapillary Renal Cell Carcinoma
Role
alias
Name
PACT
Role
alias
Name
PAPILLARY CARCINOMA OF THYROID
Role
alias
Name
PDMI
Role
alias
Name
PNDM
Role
alias
Name
PTC
Role
alias
Name
Papillary Renal Cell Carcinoma Type 1
Role
alias
Name
RCC
Role
alias
Name
Renal Carcinoma
Role
alias
Name
Renal Cell Carcinoma, Chromophobe
Role
alias
Name
Renal Cell Carcinoma, Papillary, 1
Role
alias
Name
T2D
Role
alias
Name
TPC
Role
alias
Name
Thyroid Adenoma
Role
alias
Name
Thyroid Cancer, Nonmedullary
Role
alias
Name
Thyroid Cancer, Papillary
Role
alias
Name
Thyroid Carcinoma, Nonmedullary, With Or Without Cell Oxyphilia
Role
alias
Name
Thyroid Follicular Adenoma
Role
alias
Name
Thyroid Gland Cancer
Role
alias
Name
Thyroid Gland Carcinoma
Role
alias
Name
Thyroid Gland Papillary Carcinoma
Role
alias
Name
Thyroid Neoplasms
Role
alias
Name
Thyroid Papillary Carcinoma
Role
alias
Name
Tndm2
Role
alias
Name
Transient Neonatal Diabetes Mellitus
Role
alias
Name
Type 2 Diabetes
Role
alias
Name
Type 2 Diabetes Mellitus
Role
alias
Name
Type Ii Diabetes
Role
alias
Name
Type Ii Diabetes Mellitus
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0000831HP:0000854HP:0000855HP:0002890HP:0002895HP:0005584HP:0005978HP:0006766HP:0006770HP:0011774HP:0011797HP:0040198
Herb
HBDIS000054HBDIS000449HBDIS000460HBDIS000772HBDIS000778HBDIS001553HBDIS002946HBDIS003549HBDIS004089HBDIS005183HBDIS007121HBDIS007523HBDIS007963HBDIS010138HBDIS011919HBDIS012434HBDIS012954HBDIS012955HBDIS012956HBDIS013449HBDIS013968HBDIS014005HBDIS014834HBDIS015064HBDIS015065HBDIS015085HBDIS015140HBDIS015141HBDIS015363HBDIS016853HBDIS016968HBDIS018066HBDIS018107HBDIS019894HBDIS020390HBDIS021548HBDIS021549HBDIS025336HBDIS025706HBDIS025707HBDIS026165HBDIS027759HBDIS027959
Me Sh
D000077273D000231D002292D003924D007333
Omim
125851125853144700188550601410603744605074606176610374610582616534616535
Umls
C0001420C0007134C0011860C0021655C0238463C0279702C0334373C1266042C1266043C1266044C1306837C1336078C1832386C1833102C1833104C1852091C1853564C2750825C3501843C3501844C4017238
Icd10
C73E11P70.2
Sym Map
SMDE00548SMDE01221SMDE01541SMDE01851SMDE03386SMDE04020SMDE04086SMDE04740SMDE07097SMDE07319SMDE07544SMDE07854SMDE07855SMDE09954SMDE10035SMDE11886SMDE11890SMDE11891SMDE12779SMDE12963SMDE13895
Do Class
DOID:0014667DOID:14566DOID:630DOID:7
Dis Ge Net
C0001420C0007115C0007134C0011847C0011860C0021655C0040136C0151468C0158981C0238463C0279702C0334373C0342277C0549473C0854110C0920563C1266042C1266043C1266044C1306837C1336078C1336839C1709457C1832386C1832387C1832544C1833102C1833104C1835887C1852091C1853564C1863925C1864623C2750825C2931899C3501843C3501844C4049328C4225292C4225293C4303593C4721429C4733333
Orphanet
319487791349988599886
Umls Sty
T033T046T047T191
Hpo Class
HP:0000119HP:0000818HP:0001939HP:0002664
Me Sh Class
C04C10C12C13C16C18C19C23F01
Etcm Disease
Diabetes Mellitus, Noninsulin-DependentDiabetes Mellitus, Permanent NeonatalDiabetes Mellitus, Transient Neonatal, 1Familial Papillary or Follicular Thyroid Carcinoma
Tcmbank Disease
10147102951134412560125661263114016142831446214469154521668717036171331729017608188441929020505207952170421935229532305824761254112558525654266872673128217286612922329356296523132385324833193456410474161646167694475779085387339126
Itcmdb Generated
ITX-DISEASE-07E36C87F6ECITX-DISEASE-0D0916A365ADITX-DISEASE-1E2CA6BAD83AITX-DISEASE-231767F0558DITX-DISEASE-26CD991E61FEITX-DISEASE-2969D2F2C2DAITX-DISEASE-2C5F085D6F7EITX-DISEASE-3B0FFBD0C4DCITX-DISEASE-4BB460F34109ITX-DISEASE-4FB4BD1531F1ITX-DISEASE-57122BFC73DEITX-DISEASE-6DBF6698B26AITX-DISEASE-7EBF9D0BD7EEITX-DISEASE-9C005EC0A0ABITX-DISEASE-A68F04E6BC62ITX-DISEASE-A78E324284DEITX-DISEASE-B262B1794748ITX-DISEASE-B394024A9812ITX-DISEASE-B77331C34C47ITX-DISEASE-BDF85C05CB38ITX-DISEASE-CD2F55262578ITX-DISEASE-CD64F09A6F35ITX-DISEASE-D4C6A86C1711ITX-DISEASE-E5C615539C37ITX-DISEASE-EA712073FD63
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v1,v2v2
Suppress
0
Page Title
Disease Diabetes Mellitus, Noninsulin-Dependent Details pageDisease Diabetes Mellitus, Permanent Neonatal Details pageDisease Diabetes Mellitus, Transient Neonatal, 1 Details pageDisease Familial Papillary or Follicular Thyroid Carcinoma Details page
Do Class Name
disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferationdisease of metabolismdisease of metabolism; genetic disease
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of metabolism/homeostasisAbnormality of metabolism/homeostasis; Abnormality of the endocrine systemAbnormality of the endocrine system; NeoplasmAbnormality of the genitourinary system; Neoplasm
Do Disease Class
disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferationdisease of metabolismgenetic disease; disease of metabolism
Hpo Disease Class
Abnormality of metabolism/homeostasisAbnormality of metabolism/homeostasis; Abnormality of the endocrine systemNeoplasm; Abnormality of the endocrine systemNeoplasm; Abnormality of the genitourinary system
Umls Disease Type
Disease or SyndromeFindingNeoplastic ProcessPathologic Function
Basic Information
Disease Name
Diabetes Mellitus, Noninsulin-Dependent
Global Category
Genetic diseases;Metabolic diseases
Anatomical Category
Endocrine diseases
Disease Name
Diabetes Mellitus, Permanent Neonatal
Global Category
Genetic diseases;Metabolic diseases;Rare diseases
Anatomical Category
Endocrine diseases;Neuronal diseases
Disease Name
Diabetes Mellitus, Transient Neonatal, 1
Global Category
Fetal diseases;Genetic diseases;Metabolic diseases;Rare diseases
Anatomical Category
Endocrine diseases
Disease Name
Familial Papillary or Follicular Thyroid Carcinoma
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Endocrine diseases
Disease Definition
DEND syndrome is a very rare, generally severe form of neonatal diabetes mellitus (NDM, see this term) characterized by a triad of developmental delay, epilepsy, and neonatal diabetes.NCI2016_02D:A benign or malignant neoplasm affecting the thyroid gland.|MSH2017_2016_08_12:Tumors or cancer of the THYROID GLAND.|HPO2016_07_04:A tumor (abnormal growth of tissue) of the thyroid gland. [HPO:probinson]|CSP2006:new abnormal thyroid tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.NCI2016_02D:A breast adenocarcinoma characterized by the presence of an intraductal papillary carcinomatous component and an invasive carcinomatous component.NCI2016_02D:A high grade carcinoma of the kidney. It is not a distinct clinicopathological entity and includes a diverse group of renal cell carcinomas which have been transformed from a lower to a higher grade.NCI2016_02D:A type of carcinoma that comprises a minority of renal cell carcinomas. It is characterized by loss of chromosomes 1 and Y. Based on the cytoplasmic characteristics of the neoplastic cells, this type of carcinoma is classified as classic (typical) or eosinophilic. It has a much better prognosis than other renal cell carcinomas.NCI2016_02D:Also known as chromophil carcinoma, it represents a minority of renal cell carcinomas. It can be hereditary or sporadic. The sporadic papillary renal cell carcinoma is characterized by trisomy of chromosomes 7, 16, and 17, and loss of chromosome Y. The peak incidence is in the sixth and seven decades. It is classified as type 1 or 2, based on the cytoplasmic volume and the thickness of the lining neoplastic cells. The prognosis is more favorable than for conventional (clear cell) renal cell carcinoma. -- 2003|HPO2016_07_04:The presence of renal cell carcinoma in the renal papilla. [HPO:probinson]NCI2016_CDISC_1602D:An adenocarcinoma with papillary growth pattern.|NCI2016_02D:A morphologic variant of adenocarcinoma. It is characterized by the presence of a papillary growth pattern. Representative examples include thyroid gland papillary carcinoma, invasive papillary breast carcinoma, and ovarian serous surface papillary adenocarcinoma.|MSH2017_2016_08_12:An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)NCI2016_NCI-GLOSS_1602D:A rare type of kidney cancer that grows and spreads quickly. It begins in the duct of Bellini in the kidney.|NCI2016_02D:Also known as collecting duct carcinoma, this is a rare type of renal carcinoma. It arises from the collecting ducts of the renal medulla, and most authors suggest that this is an aggressive tumor.NCI2016_NCI-GLOSS_1602D:Cancer that forms in follicular cells in the thyroid and grows in small finger-like shapes. It grows slowly, is more common in women than in men, and often occurs before age 45. It is the most common type of thyroid cancer.|NCI2016_02D:A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. Radiation exposure is a risk factor and it is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include thyroid ultrasound and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance.|HPO2016_07_04:The presence of a papillary adenocarcinoma of the thyroid gland. [HPO:probinson]NCI2016_NCI-GLOSS_1602D:The most common type of kidney cancer. It begins in the lining of the renal tubules in the kidney. The renal tubules filter the blood and produce urine.|NCI2016_02D:A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor may metastasize to unusual sites and late metastasis is common.|HPO2016_07_04:A subtype of renal cell carcinoma thought to originate from mature renal tubular cells in the proximal tubule of the nehpron. [DDD:rscott]NCI2016_NICHD_1602D:A chronic condition characterized by insulin resistance and/or insufficient production of insulin by the pancreas.|NCI2016_02D:A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.|MSH2017_2016_08_12:A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.|MEDLINEPLUS_20151021:<p><a href='https://www.nlm.nih.gov/medlineplus/diabetes.html'>Diabetes</a> means your blood glucose, or <a href='https://www.nlm.nih.gov/medlineplus/bloodsugar.html'>blood sugar</a>, levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to <a href='https://www.nlm.nih.gov/medlineplus/diabetescomplications.html'>serious problems</a> with your <a href='https://www.nlm.nih.gov/medlineplus/diabeticheartdisease.html'>heart</a>, <a href='https://www.nlm.nih.gov/medlineplus/diabeticeyeproblems.html'>eyes</a>, <a href='https://www.nlm.nih.gov/medlineplus/diabetickidneyproblems.html'>kidneys</a>, <a href='https://www.nlm.nih.gov/medlineplus/diabeticnerveproblems.html'>nerves</a>, and gums and teeth.</p> <p>You have a higher risk of type 2 diabetes if you are older, obese, have a family history of diabetes, or do not exercise. Having <a href='https://www.nlm.nih.gov/medlineplus/prediabetes.html'>prediabetes</a> also increases your risk. Prediabetes means that your blood sugar is higher than normal but not high enough to be called diabetes.</p> <p>The symptoms of type 2 diabetes appear slowly. Some people do not notice symptoms at all. The symptoms can include</p> <ul> <li>Being very thirsty</li> <li>Urinating often</li> <li>Feeling very hungry or tired</li> <li>Losing weight without trying</li> <li>Having sores that heal slowly</li> <li>Having blurry eyesight</li> </ul> <p>A blood test can show if you have diabetes. Many people can manage their diabetes through <a href='https://www.nlm.nih.gov/medlineplus/diabeticdiet.html'>healthy eating</a>, physical activity, and blood glucose testing. Some people also need to take <a href='https://www.nlm.nih.gov/medlineplus/diabetesmedicines.html'>diabetes medicines</a>.</p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:A type of diabetes mellitus initially characterized by insulin resistance and hyperinsulinemia and subsequently by glucose interolerance and hyperglycemia. [HPO:probinson]|CSP2006:subclass of diabetes mellitus that is not insulin responsive or dependent; characterized initially by insulin resistance and hyperinsulinemia and eventually by glucose intolerance, hyperglycemia, and overt diabetes; type II diabetes mellitus is no longer considered a disease exclusively found in adults; patients seldom develop ketosis but often exhibit obesity.NCI2016_NICHD_1602D:A malignant neoplasm arising from the renal parenchyma.|NCI2016_NCI-GLOSS_1602D:The most common type of kidney cancer. It begins in the lining of the renal tubules in the kidney. The renal tubules filter the blood and produce urine.|NCI2016_CDISC_1602D:A malignant neoplasm arising from renal parenchyma.|NCI2016_02D:A carcinoma arising from the renal parenchyma. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy.|MSH2017_2016_08_12:A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.|HPO2016_07_04:A type of carcinoma of the kidney with origin in the epithelium of the proximal convoluted renal tubule. [HPO:probinson]|CSP2006:cancerous kidney tumor composed of tubular cells; usually occurs in middle age or later in life; primary symptom is hematuria; nephrectomy is usually necessary.NCI2016_NICHD_1602D:Decreased sensitivity to circulating insulin which may result in acanthosis nigricrans, elevated insulin level or hyperglycemia.|NCI2016_02D:Decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia.|MSH2017_2016_08_12:Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.|HPO2016_07_04:Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [HPO:probinson]Permanent neonatal diabetes mellitus (PNDM) is a monogenic form of neonatal diabetes (NDM, see this term) characterized by persistent hyperglycemia within the first 12 months of life in general, requi
Me Sh Disease Class
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System DiseasesEndocrine System DiseasesEndocrine System Diseases; Nervous System Diseases; Nutritional and Metabolic Diseases; Pathological Conditions, Signs and SymptomsFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; NeoplasmsNeoplasmsNeoplasms; Endocrine System DiseasesNervous System DiseasesNutritional and Metabolic DiseasesNutritional and Metabolic Diseases; Endocrine System DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases; Behavior and Behavior Mechanisms; Endocrine System Diseases
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System DiseasesEndocrine System DiseasesNeoplasmsNeoplasms; Endocrine System DiseasesNeoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital DiseasesNervous System DiseasesNutritional and Metabolic DiseasesNutritional and Metabolic Diseases; Endocrine System DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases; Behavior and Behavior MechanismsPathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
Umls Semantic Type Name
Disease or SyndromeFindingNeoplastic ProcessPathologic Function