DiseaseID 3368
动脉粥样斑块
disease
MSH2017_2016_08_12:An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the h
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Disease: 1Experiment: 5Formula: 24Herb: 12Symptom: 12Target: 24Links: 77
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3368
- Core Entity Id
- 59566
- Source Entity Count
- 1
- Preferred Name
- Atheroma
- Name Cn
- 动脉粥样斑块
- Name Pinyin
- Dong Mai Zhou Yang Ban Kuai
- Name En
- Atheroma
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Acquired Abnormality
- Disgenet Type
- disease
- Mesh Class
- Cardiovascular DiseasesCardiovascular Diseases; Digestive System Diseases; Pathological Conditions, Signs and SymptomsCardiovascular Diseases; Pathological Conditions, Signs and SymptomsPathological Conditions, Signs and Symptoms
- Do Class
- disease of anatomical entity
- Hpo Class
- Abnormality of the cardiovascular system
- Mesh Class Name
- Cardiovascular DiseasesPathological Conditions, Signs and SymptomsPathological Conditions, Signs and Symptoms; Cardiovascular DiseasesPathological Conditions, Signs and Symptoms; Digestive System Diseases; Cardiovascular Diseases
- Hpo Class Name
- Abnormality of the cardiovascular system
- Do Class Name
- disease of anatomical entity
- Disease Definition
- MSH2017_2016_08_12:An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.|CSP2006:imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow.
- Version
- v1,v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Atheroma
Role
preferred
Name
Arteriosclerosis
Role
preferred
Name
Coronary Arteriosclerosis
Role
preferred
Name
Coronary Artery Disease
Role
preferred
Name
Coronary Artery Disease, Autosomal Dominant, 1
Role
preferred
Name
Hydatidiform Mole, Recurrent, 2
Role
preferred
Name
Plaque, Atherosclerotic
Role
preferred
Name
Acute Coronary Insufficiency
Role
preferred
Name
Acute Ischemic Heart Disease
Role
preferred
Name
Arterial Fatty Streak
Role
preferred
Name
Arteriolosclerosis
Role
preferred
Name
Arteriosclerotic Cardiovascular Disease, Nos
Role
preferred
Name
Arteriovascular Degeneration
Role
preferred
Name
Atherogenesis
Role
preferred
Name
Atherosclerosis
Role
preferred
Name
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2 (disorder)
Role
preferred
Name
Cardiac Cirrhosis
Role
preferred
Name
Chronic Myocardial Ischemia
Role
preferred
Name
Coronary Artery Atheroma
Role
preferred
Name
Coronary Heart Disease
Role
preferred
Name
Fibroatheroma
Role
preferred
Name
Myocardial Ischemia
Role
preferred
Name
Type Iv Atherosclerotic Lesion
Role
preferred
Name
Vascular Degeneration
Role
preferred
Name
Acute Ischaemic Heart Disease, Unspecified
Role
alias
Name
Adcad2
Role
alias
Name
Arteriosclerotic Cardiovascular Disease
Role
alias
Name
Atheromatosis
Role
alias
Name
Atherosclerotic Cardiovascular Disease
Role
alias
Name
Atherosclerotic Cardiovascular Disease, So Described
Role
alias
Name
Atherosclerotic Heart Disease
Role
alias
Name
Chronic Ischaemic Heart Disease
Role
alias
Name
Chronic Ischaemic Heart Disease, Unspecified
Role
alias
Name
Coronary Artery Atherosclerosis
Role
alias
Name
Coronary Artery Disease, Autosomal Dominant 2
Role
alias
Name
Coronary Atherosclerosis
Role
alias
Name
Coronary Disease
Role
alias
Name
Disease, Coronary Heart
Role
alias
Name
HYDATIDIFORM MOLE, COMPLETE
Role
alias
Name
HYDM2
Role
alias
Name
Ischaemic Heart Diseases
Role
alias
Name
Narrowing And Hardening of Arteries
Role
alias
Name
Nutmeg Liver
Role
alias
Name
Plaque Build-Up In Arteries Supplying Blood To Heart
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0001677HP:0002621HP:0002635
Herb
HBDIS000237HBDIS000273HBDIS000668HBDIS000669HBDIS001047HBDIS003366HBDIS003597HBDIS005691HBDIS005693HBDIS005694HBDIS005723HBDIS005725HBDIS012321HBDIS013169HBDIS014332HBDIS014587HBDIS015924HBDIS018581HBDIS018840HBDIS020408HBDIS020409HBDIS021948HBDIS027621HBDIS029342
Me Sh
D003327D050197D050379D058226
Omim
608320610947614293
Umls
C0004153C0010068C1842247C1956346C2936350C3280352
Icd10
I24.9I25I25.0I25.9I70
Sym Map
SMDE01681SMDE06037SMDE06115SMDE07572SMDE07573SMDE07574SMDE07576SMDE11222SMDE12207
Do Class
DOID:7
Dis Ge Net
C0003850C0004153C0010054C0010068C0015697C0085699C0151744C0264683C0264693C0264694C0264954C0264956C0878486C1281300C1510446C1563937C1842247C1956346C1970440C2936350C2936351C3280352C3665365C4703375
Umls Sty
T020T031T046T047
Hpo Class
HP:0001626
Me Sh Class
C06C14C23
Etcm Disease
Coronary Artery Disease, Autosomal Dominant, 1Hydatidiform Mole, Recurrent, 2
Tcmbank Disease
1029103114318153071577615830164281837218460202852196223364237244862497924992257362578825911260582707229897365354585758745878588871
Itcmdb Generated
ITX-DISEASE-05687F8793C3ITX-DISEASE-1D1625322786ITX-DISEASE-24D5595511A7ITX-DISEASE-2AE426B46182ITX-DISEASE-44F00A508DCFITX-DISEASE-49D35A97BAE4ITX-DISEASE-4D9FF9CF95B5ITX-DISEASE-6B3960123A16ITX-DISEASE-C263C6EFB45AITX-DISEASE-C5D110E854AAITX-DISEASE-D5DAD4D5CE05
Attributes
Merged source attributes and domain-specific metadata.
Version
v1,v2v2
Suppress
0
Page Title
Disease Coronary Artery Disease, Autosomal Dominant, 1 Details pageDisease Hydatidiform Mole, Recurrent, 2 Details page
Do Class Name
disease of anatomical entity
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of the cardiovascular system
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of the cardiovascular system
Umls Disease Type
Acquired AbnormalityBody SubstanceDisease or SyndromePathologic Function
Basic Information
Disease Name
Coronary Artery Disease, Autosomal Dominant, 1
Global Category
Genetic diseases
Anatomical Category
Cardiovascular diseases
Disease Name
Hydatidiform Mole, Recurrent, 2
Global Category
Cancer diseases;Fetal diseases;Genetic diseases;Rare diseases
Anatomical Category
Reproductive diseases
Disease Definition
MSH2017_2016_08_12:An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.|CSP2006:imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow.MSH2017_2016_08_12:Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).|HPO2016_07_04:Coronary artery disease, also called atherosclerotic heart disease, is the result of atheromatous plaques within the coronary arteries leading to myocardial ischemia and infarction. [HPO:curators]NCI2016_02D:A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries, to obstruction by a thrombus, or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (myocardial infarction).|MSH2017_2016_08_12:A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).|CSP2006:blood deficiency in the myocardium caused by a constriction or obstruction of its blood vessels; frequently occurs in conjunction with hypoxia, which is reduction in oxygen supply.NCI2016_02D:A vascular disorder characterized by thickening and hardening of the walls of the arteries.|MSH2017_2016_08_12:Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.|HPO2016_07_04:Sclerosis (hardening) of the arteries with increased thickness of the wall of arteries as well as increased stiffness and a loss of elasticity. [HPO:probinson]|CSP2006:thickening and loss of elasticity of arterial walls; atherosclerosis is the most common form of arteriosclerosis and involves lipid deposition and thickening of the intimal cell layers within arteries; additional forms of arteriosclerosis involve calcification of the media of muscular arteries (Monkeberg medial calcific sclerosis) and thickening of the walls of small arteries or arterioles due to cell proliferation or hyaline deposition (arteriolosclerosis).NCI2016_02D:Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.|MSH2017_2016_08_12:A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.|MEDLINEPLUS_20151021:<p>Atherosclerosis is a disease in which plaque builds up inside your arteries. Plaque is a sticky substance made up of fat, <a href='https://www.nlm.nih.gov/medlineplus/cholesterol.html'>cholesterol</a>, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries. That limits the flow of oxygen-rich blood to your body.</p> <p>Atherosclerosis can lead to serious problems, including</p> <ul> <li><a href='https://www.nlm.nih.gov/medlineplus/coronaryarterydisease.html'>Coronary artery disease</a>. These arteries supply blood to your heart. When they are blocked, you can suffer angina or a heart attack.</li> <li><a href='https://www.nlm.nih.gov/medlineplus/carotidarterydisease.html'>Carotid artery disease</a>. These arteries supply blood to your brain. When they are blocked you can suffer a <a href='https://www.nlm.nih.gov/medlineplus/ischemicstroke.html'>stroke</a>.</li> <li><a href='https://www.nlm.nih.gov/medlineplus/peripheralarterialdisease.html'>Peripheral arterial disease</a>. These arteries are in your arms, legs and pelvis. When they are blocked, you can suffer from numbness, pain and sometimes infections.</li> </ul> <p>Atherosclerosis usually doesn't cause symptoms until it severely narrows or totally blocks an artery. Many people don't know they have it until they have a medical emergency.</p> <p>A physical exam, imaging, and other diagnostic tests can tell if you have it. Medicines can slow the progress of plaque buildup. Your doctor may also recommend procedures such as <a href='https://www.nlm.nih.gov/medlineplus/angioplasty.html'>angioplasty</a> to open the arteries, or surgery on the <a href='https://www.nlm.nih.gov/medlineplus/coronaryarterybypasssurgery.html'>coronary</a> or carotid arteries. Lifestyle changes can also help. These include following a healthy diet, getting regular exercise, maintaining a healthy weight, quitting smoking, and managing stress. </p> <p >NIH: National Heart, Lung, and Blood Institute</p>|HPO2016_07_04:A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls of medium-sized and large arteries and can lead to arterial stenosis with reduced or blocked blood flow. [HPO:probinson]|CSP2006:age, lifestyle, diet, and gene related degeneration of arteries due to deposition of lipoid plaques (atheromas) on inner arterial walls; main cause of coronary artery disease, a leading cause of death.|CHV2011_02:deposition of cholesterol and lipid in the inner layer of the blood vessel|CHV2011_02:deposition of cholesterol and lipid in the inner layer of the blood vessel|CHV2011_02:deposition of cholesterol and lipid in the inner layer of the blood vessel|CHV2011_02:deposition of cholesterol and lipid in the inner layer of the blood vesselNCI2016_02D:Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)|MSH2017_2016_08_12:Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.|MEDLINEPLUS_20151021:<p>Coronary artery disease (CAD) is the most common type of heart disease. It is the leading cause of death in the United States in both men and women.</p> <p>CAD happens when the arteries that supply blood to heart muscle become hardened and narrowed. This is due to the buildup of <a href='https://www.nlm.nih.gov/medlineplus/cholesterol.html'>cholesterol</a> and other material, called plaque, on their inner walls. This buildup is called <a href='https://www.nlm.nih.gov/medlineplus/atherosclerosis.html'>atherosclerosis</a>. As it grows, less blood can flow through the arteries. As a result, the heart muscle can't get the blood or oxygen it needs. This can lead to chest pain (<a href='https://www.nlm.nih.gov/medlineplus/angina.html'>angina</a>) or a <a href='https://www.nlm.nih.gov/medlineplus/heartattack.html'>heart attack</a>. Most heart attacks happen when a <a href='https://www.nlm.nih.gov/medlineplus/bloodclots.html'>blood clot</a> suddenly cuts off the hearts' blood supply, causing permanent heart damage. </p> <p>Over time, CAD can also weaken the heart muscle and contribute to <a href='https://www.nlm.nih.gov/medlineplus/heartfailure.html'>heart failure</a> and <a href='https://www.nlm.nih.gov/medlineplus/arrhythmia.html'>arrhythmias</a>. Heart failure means the heart can't pump blood well to the rest of the body. Arrhythmias are changes in the normal beating rhythm of the heart. </p> <p >NIH: National Heart, Lung, and Blood Institute</p>|HPO2016_07_04:Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries, which increases the risk of myocardial ischemia. [HPO:probinson]NCI2016_CDISC_1602D:Fatty tissue which is deposited in the inner lining of the arterial wall. (NCI)|NCI2016_02D:Fatty tissue which is deposited in the inner lining of the arterial wall.|MSH2017_2016_08_12:Lesions formed within the walls of ARTERIES.|CSP2006:yellowish plaques containing cholesterol, lipoid material, and lipophages formed within the intima and inner media of large and medium-sized arteries in atherosclerosis.
Me Sh Disease Class
Cardiovascular DiseasesCardiovascular Diseases; Digestive System Diseases; Pathological Conditions, Signs and SymptomsCardiovascular Diseases; Pathological Conditions, Signs and SymptomsPathological Conditions, Signs and Symptoms
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Cardiovascular DiseasesPathological Conditions, Signs and SymptomsPathological Conditions, Signs and Symptoms; Cardiovascular DiseasesPathological Conditions, Signs and Symptoms; Digestive System Diseases; Cardiovascular Diseases
Umls Semantic Type Name
Acquired AbnormalityBody SubstanceDisease or SyndromePathologic Function