DiseaseID 3254
骨髓纤维化
disease
NCI2016_NCI-GLOSS_1602D:A disorder in which the bone marrow is replaced by fibrous tissue.|NCI2016_02D:A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
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Disease: 1Formula: 4Herb: 7Symptom: 8Target: 24Links: 43
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3254
- Core Entity Id
- 59437
- Source Entity Count
- 1
- Preferred Name
- Myelofibrosis
- Name Cn
- 骨髓纤维化
- Name Pinyin
- Gu Sui Xian Wei Hua
- Name En
- Myelofibrosis
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Hemic and Lymphatic DiseasesHemic and Lymphatic Diseases; Neoplasms; Pathological Conditions, Signs and Symptoms
- Do Class
- disease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Abnormality of blood and blood-forming tissues
- Mesh Class Name
- Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
- Hpo Class Name
- Abnormality of blood and blood-forming tissues
- Do Class Name
- disease of anatomical entity; disease of cellular proliferation
- Disease Definition
- NCI2016_NCI-GLOSS_1602D:A disorder in which the bone marrow is replaced by fibrous tissue.|NCI2016_02D:A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion as part of the chronic myeloproliferative disorders (chronic idiopathic myelofibrosis), a manifestation of acute myeloid leukemia (acute panmyelosis with myelofibrosis), or a secondary phenomenon due to bone marrow involvement by a metastatic tumor (e.g., metastatic breast carcinoma). --2003|HPO2016_07_04:Replacement of bone marrow by fibrous tissue. [HPO:probinson]|CSP2006:replacement of the bone marrow by fibrous tissue, occurring in association with a myeloproliferative disorder or secondary to another unrelated condition.
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Myelofibrosis
Role
preferred
Name
Primary Myelofibrosis
Role
preferred
Name
Myelofibrosis Due To Another Disorder
Role
preferred
Name
Osteomyelofibrosis
Role
preferred
Name
MMM
Role
alias
Name
MYELOFIBROSIS WITH MYELOID METAPLASIA
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0011974
Herb
HBDIS000084HBDIS002020HBDIS005390HBDIS012545
Me Sh
D055728
Omim
254450
Umls
C0001815C0026987
Icd10
D47.4D75.81
Sym Map
SMDE04455SMDE12452
Do Class
DOID:14566DOID:7
Dis Ge Net
C0001815C0026987C0242006C0948968
Umls Sty
T047T191
Hpo Class
HP:0001871
Me Sh Class
C04C15C23
Etcm Disease
Myelofibrosis
Tcmbank Disease
1352513667243932449530041
Itcmdb Generated
ITX-DISEASE-72869DB39279ITX-DISEASE-9C3E9212B1A5
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v2
Suppress
0
Page Title
Disease Myelofibrosis Details page
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Abnormality of blood and blood-forming tissues
Umls Disease Type
Disease or SyndromeNeoplastic Process
Basic Information
Disease Name
Myelofibrosis
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Blood diseases
Disease Definition
NCI2016_NCI-GLOSS_1602D:A disorder in which the bone marrow is replaced by fibrous tissue.|NCI2016_02D:A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion as part of the chronic myeloproliferative disorders (chronic idiopathic myelofibrosis), a manifestation of acute myeloid leukemia (acute panmyelosis with myelofibrosis), or a secondary phenomenon due to bone marrow involvement by a metastatic tumor (e.g., metastatic breast carcinoma). --2003|HPO2016_07_04:Replacement of bone marrow by fibrous tissue. [HPO:probinson]|CSP2006:replacement of the bone marrow by fibrous tissue, occurring in association with a myeloproliferative disorder or secondary to another unrelated condition.NCI2016_NCI-GLOSS_1602D:A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is marked by an enlarged spleen and progressive anemia.|NCI2016_02D:A chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, proliferation of atypical megakaryocytes and granulocytes in the bone marrow, anemia, splenomegaly, and extramedullary hematopoiesis. (WHO, 2001)|MSH2017_2016_08_12:A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Me Sh Disease Class
Hemic and Lymphatic DiseasesHemic and Lymphatic Diseases; Neoplasms; Pathological Conditions, Signs and Symptoms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Disease or SyndromeNeoplastic Process