DiseaseID 25851

Birt-Hogg-Dubé综合征

Birt-Hogg-Dube Syndrome

NCI2016_NCI-GLOSS_1602D:An inherited condition in which benign tumors develop in hair follicles on the head, chest, back, and arms. People who have this disorder may be at increased risk of developing colon or kidney can

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Disease: 1Formula: 12Herb: 12Symptom: 1Target: 18Links: 49
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Record Fields

Scalar fields from the final disease record.

Disease Id
25851
Core Entity Id
118419
Source Entity Count
1
Preferred Name
Birt-Hogg-Dube Syndrome
Name Cn
Birt-Hogg-Dubé综合征
Name Pinyin
Birt-hogg-dubé Zong He Zheng
Name En
Birt-Hogg-Dube Syndrome
Name Latin
Bilingual Status
complete
Disease Type
Umls Disease Type
Disgenet Type
Mesh Class
Do Class
Hpo Class
Mesh Class Name
Hpo Class Name
Do Class Name
Disease Definition
NCI2016_NCI-GLOSS_1602D:An inherited condition in which benign tumors develop in hair follicles on the head, chest, back, and arms. People who have this disorder may be at increased risk of developing colon or kidney cancer.|NCI2016_02D:A rare genetic syndrome with an autosomal dominant pattern of inheritance. It is caused by a mutation in the FLCN gene which encodes the protein folliculin. Clinical signs include multiple benign growths of the skin and lungs that begin to manifest in the second or third decade of life. The clinical course is characterized by the progressive growth of new and existing neoplasms. In those with mutations in both copies of FLCN, the kidneys may also be affected by the growth of benign or malignant neoplasms.|MSH2017_2016_08_12:Autosomal dominant neoplastic syndrome characterised by genodermatosis, lung cysts, spontaneous and recurrent PNEUMOTHORAX; and RENAL CANCER. It is associated with mutations in the folliculin protein gene (FLCN protein).
Version
v1
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Birt-Hogg-Dube Syndrome
Role
preferred

Cross References

Trusted external identifiers retained for this final record.

Umls
C0346010
Med Dra
10067736
Sym Map
SMDE00646
Orphanet
122
Etcm Disease
Birt-Hogg-Dube Syndrome
Itcmdb Generated
ITX-DISEASE-B9688B9C54F4

Attributes

Merged source attributes and domain-specific metadata.

Version
v1
Suppress
0
Page Title
Disease Birt-Hogg-Dube Syndrome Details page
Basic Information
Disease Name
Birt-Hogg-Dube Syndrome
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Nephrological diseases;Respiratory diseases;Skin diseases
Disease Definition
NCI2016_NCI-GLOSS_1602D:An inherited condition in which benign tumors develop in hair follicles on the head, chest, back, and arms. People who have this disorder may be at increased risk of developing colon or kidney cancer.|NCI2016_02D:A rare genetic syndrome with an autosomal dominant pattern of inheritance. It is caused by a mutation in the FLCN gene which encodes the protein folliculin. Clinical signs include multiple benign growths of the skin and lungs that begin to manifest in the second or third decade of life. The clinical course is characterized by the progressive growth of new and existing neoplasms. In those with mutations in both copies of FLCN, the kidneys may also be affected by the growth of benign or malignant neoplasms.|MSH2017_2016_08_12:Autosomal dominant neoplastic syndrome characterised by genodermatosis, lung cysts, spontaneous and recurrent PNEUMOTHORAX; and RENAL CANCER. It is associated with mutations in the folliculin protein gene (FLCN protein).