Meta AnalysisID 9

针刺和艾灸对乳腺癌相关淋巴水肿的影响：随机对照试验的系统评价和Meta分析

CRD42021241686

We conducted this study to determine whether acupuncture and/or moxibustion is safe and effective measure for patients with breast cancer associated lymphedema. P：Patients were women with lymphedema as a result of surger

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Meta Analysis Id: 9
Evidence Id: 8567
Core Evidence Id: 8567
Source Meta Analysis Id: 9
Herb2 Meta Analysis Id: HBMA000009
Crd Id: CRD42021241686
Title: Effects of Acupuncture and Moxibustion on Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis of randomized controlled trials.
Review Question: We conducted this study to determine whether acupuncture and/or moxibustion is safe and effective measure for patients with breast cancer associated lymphedema. P：Patients were women with lymphedema as a result of surgery, chemotherapy, and/or radiation for breast cancer. There were no restrictions on participants' breast cancer stage, lymphedema grade, age, or country. I：The treatment group was treated with acupuncture and/or moxibustion without restriction of manipulation techniques. Only needle acupuncture was allowed, and other forms of acupuncture (such as laser acupuncture or electroacupuncture) were not allowed. Only burning Artemisia vulgaris was allowed in moxibustion treatment, and no other herbs were allowed. C: The control group could receive any treatments except acupuncture or moxibustion. O: The primary outcome of the study was the improvement in the degree of edema, which was assessed by measuring the circumference or volume of the arm or the fluid content in the limb. The secondary outcomes included clinical efficacy, Visual Analog Score (VAS) for swelling/ pain, Range Of Motion, Quality Of Life, and the incidences of adverse events related to AM (such as bruising, hematoma, pain, allergy, scalding, local infection, coughing, and nausea). S: The Studies were designed as clinical randomized controlled trials (RCTs).
Study Type Included: Randomized controlled trials
Condition Being Studied: Breast cancer is the most frequently diagnosed cancer among women, and its incidence is gradually increasing. However, the improvement in survival observed in recent decades led to an increased incidence of long-term complications related to the treatments. Among them, breast cancer related lymphedema(BRCL) is one of the most common problems in breast cancer survivors who undergo breast surgery and/or radiation, and it has tremendous implications on quality of life and upper limb function. Thus, limiting the development of edema and improving symptoms have become a common challenge faced by clinicians and patients. Current treatments for BRCL include manual lymphatic drainage, compression bandaging, exercise, education for the reduction phase, and the use of fitted compression garments during maintenance, but the efficacy of these measures is still uncertain. Acupuncture and moxibustion , as a significant component of Traditional Chinese Medicine, has played a full advantage in the treatment of various diseases for thousands of years. Clinically, acupuncture and moxibustion can be used alone or in combination. Some studies demonstrated that AM for BCRL may stabilize symptoms and reduce arm circumference. Some studies suggest that AM was well tolerated, but it did not significantly change arm circumference in BCRL.
Participant: Patients were women with lymphedema as a result of surgery, chemotherapy, and/or radiation for breast cancer. There were no restrictions on participants' breast cancer stage, lymphedema grade, age, or country.
Animal
Human Disease Modelled
Intervention: The treatment group was treated with acupuncture and/or moxibustion without restriction of manipulation techniques. Only needle acupuncture was allowed, and other forms of acupuncture (such as laser acupuncture or electroacupuncture) were not allowed. Only burning Artemisia vulgaris was allowed in moxibustion treatment, and no other herbs were allowed.
Comparator Control: The control group could receive any treatments except acupuncture or moxibustion.
Main Outcome: The primary outcome of the study was the improvement in the degree of edema, which was assessed by measuring the circumference or volume of the arm or the fluid content in the limb. Measures of effect The degree of reduction in arm circumference (expressed in cm or efficiency).
Outcome Measure
Additional Outcome: The secondary outcomes included clinical efficacy, Visual Analog Score (VAS) for swelling/ pain, Range Of Motion, Quality Of Life, and the incidences of adverse events related to AM (such as bruising, hematoma, pain, allergy, scalding, local infection, coughing, and nausea). Measures of effect A reduction in pain or swelling scores. Increased motion of the shoulder. Improvement in quality of life
Study Method: Intervention, Meta-analysis, Systematic review
Keyword: Acupuncture Therapy; Breast Neoplasms; Female; Humans; Lymphedema; Moxibustion; Randomized Controlled Trials as Topic
Contact: Yu Gao [email protected]
Organisational Affiliation: Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Funding Source: 13th Five-Year National Science and Technology Major Project for New Drugs（No: 2019ZX09734001）
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language: English
Country: China
Review Stage: Review Ongoing
First Submission Date: 2021-03-14
Registration Date: 2021-04-14
Anticipated Start Date: 2021-01-24
Anticipated Completion Date: 2021-05-15
Title Cn: 针刺和艾灸对乳腺癌相关淋巴水肿的影响：随机对照试验的系统评价和Meta分析
Title En: Effects of Acupuncture and Moxibustion on Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis of randomized controlled trials.
Bilingual Status: complete