Meta AnalysisID 7063
石榴汁补充对C反应蛋白水平的影响：基于随机对照试验数据的GRADE评估系统评价和剂量反应更新Meta分析
CRD42023460399
Will pomegranate juice supplementation have an effect on C-reactive protein levels? What is the best dosage of pomegranate juice to reduce protein CRP? What is the best duration of pomegranate juice supplementation to re
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7063
- Evidence Id
- 15621
- Core Evidence Id
- 15621
- Source Meta Analysis Id
- 7042
- Herb2 Meta Analysis Id
- HBMA007042
- Crd Id
- CRD42023460399
- Title
- The effect of Pomegranate juice supplementation on C-reactive protein levels: GRADE-assessed systematic review and dose-response updated meta-analysis of data from randomized controlled trials
- Review Question
- Will pomegranate juice supplementation have an effect on C-reactive protein levels? What is the best dosage of pomegranate juice to reduce protein CRP? What is the best duration of pomegranate juice supplementation to reduce protein CRP?
- Study Type Included
- Randomized controlled trials
- Condition Being Studied
- C-reactive protein (CRP) is an acute-phase protein produced by interleukin-6 (IL-6)-dependent liver biosynthesis. This serves as an indicator that levels were significantly elevated in response to injury, infection and inflammatory disease. As CRP is used as a clinical marker of inflammation, elevated CRP levels are known to be a strong independent predictor of cardiovascular disease and play an important role in the pathophysiology of cardiovascular disease.
- Participant
- To be considered, studies had to meet our eligibility criteria, which were as follows: 1) participants had to be adults aged 18 or older who had consumed pomegranate juice for any purpose, 2) the studies had to involve the use of any form of Ginseng supplements, 3) the studies had to use parallel and/or crossover randomized controlled trials to measure the lipid profile, and 4) the studies had to report comparisons between an intervention group and a control group.
- Animal
- Human Disease Modelled
- Intervention
- The effect of consuming pomegranate juice
- Comparator Control
- Use of placebo or control diet.
- Main Outcome
- Serum and plasma CRP levels(mg/dl)
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- C-Reactive Protein; Dietary Supplements; Fruit and Vegetable Juices; Humans; Pomegranate; Randomized Controlled Trials as Topic
- Contact
- mostafa shahraki jazinaki [email protected]
- Organisational Affiliation
- Mashhad University of Medical Sciences
- Funding Source
- This review will not be supported by any financial grant.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-04
- Registration Date
- 2023-09-15
- Anticipated Start Date
- 2023-06-14
- Anticipated Completion Date
- 2024-06-13
- Title Cn
- 石榴汁补充对C反应蛋白水平的影响：基于随机对照试验数据的GRADE评估系统评价和剂量反应更新Meta分析
- Title En
- The effect of Pomegranate juice supplementation on C-reactive protein levels: GRADE-assessed systematic review and dose-response updated meta-analysis of data from randomized controlled trials
- Bilingual Status
- complete