Meta AnalysisID 7004

蒺藜、双叉藻与壳聚糖复方对男性不育症患者精子浓度的疗效评价:一项系统评价与Meta分析

CRD42023417181

1. What is the effect of Tribulus terrestris, Ecklonia bicyclis and Chitosan oligosaccharides combination therapy on sperm concentration in infertile male subjects as compared to placebo therapy?

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Record Fields

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Meta Analysis Id
7004
Evidence Id
15562
Core Evidence Id
15562
Source Meta Analysis Id
6990
Herb2 Meta Analysis Id
HBMA006990
Crd Id
CRD42023417181
Title
Evaluation of efficacy of Tribulus terrestris, Ecklonia bicyclis and Chitosan combination on sperm concentration in male infertility patients: A systematic review and meta-analysis
Review Question
1. What is the effect of Tribulus terrestris, Ecklonia bicyclis and Chitosan oligosaccharides combination therapy on sperm concentration in infertile male subjects as compared to placebo therapy?
Study Type Included
Only randomized controlled studies will be included
Condition Being Studied
Male infertility is a growing concern in the modern world. Infertility is defined as the inability to conceive a child after a year of regular unprotected sexual intercourse. Approximately 15% of couples worldwide are affected by infertility, and male factor infertility is responsible for 30-50% of these cases.
Participant
Inclusion criteria 1. Male subjects 2. Subjects suffering from infertility or associated complications Exclusion criteria: 1. Animals with induced infertility.
Animal
Human Disease Modelled
Intervention
Inclusion criteria: 1. The intervention group must receive Tribulus terrestris, Ecklonia bicyclis and Chitosan oligosaccharides combination supplement 2. The supplement must be provided through oral route of administration Exclusion criteria: 1. The intervention group receives supplement other than Tribulus terrestris, Ecklonia bicyclis and Chitosan oligosaccharides therapy
Comparator Control
Inclusion criteria: 1. The intervention group must receive placebo or another supplement. 2. The supplement must be provided through oral route of administration
Main Outcome
1. Change in sperm concentration from baseline till end of study
Outcome Measure
Additional Outcome
Not applicable
Study Method
Meta-analysis, Systematic review
Keyword
Chitosan; Humans; Infertility, Male; Male; Oligosaccharides; Seeds; Tribulus
Contact
Vishal Dubey [email protected]
Organisational Affiliation
Scientific and Medical Affairs Department, Sundyota Numandis Group of Companies, Gujarat, India.
Funding Source
Not applicable
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
India
Review Stage
Review Ongoing
First Submission Date
2023-04-14
Registration Date
2023-04-25
Anticipated Start Date
2023-03-30
Anticipated Completion Date
2023-06-01
Title Cn
蒺藜、双叉藻与壳聚糖复方对男性不育症患者精子浓度的疗效评价:一项系统评价与Meta分析
Title En
Evaluation of efficacy of Tribulus terrestris, Ecklonia bicyclis and Chitosan combination on sperm concentration in male infertility patients: A systematic review and meta-analysis
Bilingual Status
complete