Meta AnalysisID 6979
番茄摄入、膳食番茄红素及血番茄红素水平与癌症发病及死亡风险的关联：前瞻性研究的综合系统评价和剂量反应Meta分析
CRD42023432400
Do tomato and lycopene affect cancer incidence and cancer mortality in adults?
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Record Fields
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- Meta Analysis Id
- 6979
- Evidence Id
- 15537
- Core Evidence Id
- 15537
- Source Meta Analysis Id
- 6960
- Herb2 Meta Analysis Id
- HBMA006960
- Crd Id
- CRD42023432400
- Title
- The associations of tomato intake, dietary lycopene, and blood levels of lycopene with cancer incidence and mortality: a comprehensive systematic review and dose-response meta-analysis of prospective studies
- Review Question
- Do tomato and lycopene affect cancer incidence and cancer mortality in adults?
- Study Type Included
- Prospective studies
- Condition Being Studied
- Cancers are known as the second cause of death in developed countries and the third cause of death in less developed countries. Lycopene is a common antioxidant component of fruits and vegetables which previous studies have paid much attention to its effects on health. Tomato is one of the main sources of lycopene. It also contains several antioxidants and fiber that may affect the risk of cancer. However, data on the associations of tomato and lycopene intake with the risk of cancer are conflicting. Therefore, there is a need for a comprehensive systematic review and dose-response meta-analysis in this regard.
- Participant
- Eligible studies conducted on adult subjects (≥ 18years) will be included.
- Animal
- Human Disease Modelled
- Intervention
- We will include cohort studies that examined the associations of tomato intake, dietary lycopene, and blood levels of lycopene with the risk of cancer and its mortality. Individuals in the highest categories of tomato intake, dietary lycopene, or blood levels of lycopene will be considered as an exposure group.
- Comparator Control
- Individuals in the lowest categories of tomato intake, dietary lycopene, and blood levels of lycopene will be considered as comparator.
- Main Outcome
- Outcome variables will be total and specific types of cancer and their mortality. We will include relative risks of these outcomes in relation to tomato and lycopene in the analysis.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adult; Eating; Humans; Incidence; Lycopene; Neoplasms; Prospective Studies; Solanum lycopersicum
- Contact
- Omid Sadeghi [email protected]
- Organisational Affiliation
- Isfahan University of Medical Sciences
- Funding Source
- Isfahan University of Medical Sciences
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-04
- Registration Date
- 2023-06-14
- Anticipated Start Date
- 2023-05-15
- Anticipated Completion Date
- 2023-08-31
- Title Cn
- 番茄摄入、膳食番茄红素及血番茄红素水平与癌症发病及死亡风险的关联：前瞻性研究的综合系统评价和剂量反应Meta分析
- Title En
- The associations of tomato intake, dietary lycopene, and blood levels of lycopene with cancer incidence and mortality: a comprehensive systematic review and dose-response meta-analysis of prospective studies
- Bilingual Status
- complete