Meta AnalysisID 6331
青娥丸治疗原发性骨质疏松症的有效性和安全性：一项系统评价与Meta分析
CRD42022299296
To explore the evidence of efficacy and safety of Qinge Pill for primary osteoporosis.
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Record Fields
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- Meta Analysis Id
- 6331
- Evidence Id
- 14889
- Core Evidence Id
- 14889
- Source Meta Analysis Id
- 6315
- Herb2 Meta Analysis Id
- HBMA006315
- Crd Id
- CRD42022299296
- Title
- Efficacy and Safety of Qinge Pill for Primary Osteoporosis: A Systematic Review and Meta-Analysis.
- Review Question
- To explore the evidence of efficacy and safety of Qinge Pill for primary osteoporosis.
- Study Type Included
- Randomized controlled trials (RCTs) will be included in this systematic review regardless of publication status and language.
- Condition Being Studied
- Primary Osteoporosis (POP) is a worldwide skeletal disorder characterized by loss of bone mass, microarchitectural deterioration, and decline in bone quality, which causes increased skeletal fragility and high risk of fractures.
- Participant
- We included trials that enrolled adults with a diagnosis of primary osteoporosis of any duration. The diagnosis of osteoporosis could have been based upon bone mineral densitometry or explicit clinical diagnostic criteria as defined by the studies.
- Animal
- Human Disease Modelled
- Intervention
- The experimental groups were treated with Qinge Pill singly or combined with control groups. And there were no restrictions on the drug dosage, frequency, or treatment time.
- Comparator Control
- Control groups could be placebo, western medicine, no intervention or other therapies without Qinge Pill.
- Main Outcome
- Clinical effective rate, bone mineral density (BMD) of hip (including femoral neck, greater trochanter, Ward's triangle) and waist, and adverse effects (overall adverse event, jaw necrosis, gastrointestinal symptoms, and general symptoms).
- Outcome Measure
- Additional Outcome
- Pain score, Estradiol, bone specific alkaline phosphatase (BALP), bone glaprotein (BGP), 25(OH)D3, β-type I collagen carboxy-terminal peptide (β-CTX), type I procollagen amino-terminal peptide (PINP).
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Bone Density Conservation Agents; Humans; Osteoporosis
- Contact
- Tong Li [email protected]
- Organisational Affiliation
- Chengdu University of Traditional Chinese Medicine
- Funding Source
- National Key Research and Development Project, China Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> 2019YFC1712500
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-01-04
- Registration Date
- 2022-02-01
- Anticipated Start Date
- 2021-12-26
- Anticipated Completion Date
- 2022-02-13
- Title Cn
- 青娥丸治疗原发性骨质疏松症的有效性和安全性：一项系统评价与Meta分析
- Title En
- Efficacy and Safety of Qinge Pill for Primary Osteoporosis: A Systematic Review and Meta-Analysis.
- Bilingual Status
- complete