Meta AnalysisID 63
蒺藜（蒺藜科）：甾体代谢物的安全性和有效性
CRD42018082377
Are Tribulus terrestris steroidal metabolites safe and effective as human dietary supplement?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 63
- Evidence Id
- 8621
- Core Evidence Id
- 8621
- Source Meta Analysis Id
- 59
- Herb2 Meta Analysis Id
- HBMA000059
- Crd Id
- CRD42018082377
- Title
- Tribulus terrestris L. (zygophyllaceae): safety and effectiveness of steroidal metabolites
- Review Question
- Are Tribulus terrestris steroidal metabolites safe and effective as human dietary supplement?
- Study Type Included
- Experimental works and clinical studies are to be selected preferentially; meta-analysis, systematic reviews and broad reviews will only be selected if essential to complement discussion of original data. There is no initial publication date limit for selected works.
- Condition Being Studied
- Dietary supplements in health and physical activity.
- Participant
- Inclusion: human and nonhuman adult populations.
- Animal
- Human Disease Modelled
- Intervention
- Dietary supplementation with Tribulus terrestris (TT) are generally provided using short-term protocols and standardized plant extracts with a certain concentration of steroidal saponins. The main populations in studies with TT are physical activity practitioners and patients with sexual dysfunctions, including human and animal models.
- Comparator Control
- Not applicable
- Main Outcome
- Changes in exercise performance and plasma markers such as hormones and signaling mediators. Measures of effect Up to four weeks long supplementation protocols with blood sampling and direct quantitative measurement of exercise performance within a defined protocol.
- Outcome Measure
- Additional Outcome
- Supplementation effects on symptoms of hypoactive sexual desire disorder (HSDD). Measures of effect Qualitative (clinical) evaluation of hypoactive sexual desire disorder parameters within four weeks of supplementation.
- Study Method
- Intervention, Pre-clinical, Systematic review
- Keyword
- Humans; Saponins; Steroids; Tribulus; Zygophyllaceae
- Contact
- Hercules Freitas [email protected]
- Organisational Affiliation
- Federal University of Rio de Janeiro https://ufrj.br/
- Funding Source
- Professor Hércules Freitas is a Ph.D. fellowship holder from Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil. Thiago Huaytalla-Silva is supported by a scholarship from National Cancer Institute José Alencar Gomes da Silva.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- An working paper is publicly available at ResearchGate: dx.doi.org/10.13140/RG.2.2.34638.77125
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran, Brazil
- Review Stage
- Review Ongoing
- First Submission Date
- 2017-11-26
- Registration Date
- 2018-01-05
- Anticipated Start Date
- 2017-03-10
- Anticipated Completion Date
- 2018-02-20
- Title Cn
- 蒺藜（蒺藜科）：甾体代谢物的安全性和有效性
- Title En
- Tribulus terrestris L. (zygophyllaceae): safety and effectiveness of steroidal metabolites
- Bilingual Status
- complete