Meta AnalysisID 283
番茄和番茄红素对紫外线诱导皮肤老化的临床特征和分子标志物的影响：干预试验的系统评价与Meta分析
CRD42022334083
What is the effect of tomato and lycopene on clinical characteristics and molecular markers of UV-Induced Skin Deterioration?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 283
- Evidence Id
- 8841
- Core Evidence Id
- 8841
- Source Meta Analysis Id
- 265
- Herb2 Meta Analysis Id
- HBMA000265
- Crd Id
- CRD42022334083
- Title
- The effect of tomato and lycopene on clinical characteristics and molecular markers of UV-Induced SkinDeterioration: A systematic review and meta-analysis of intervention trials
- Review Question
- What is the effect of tomato and lycopene on clinical characteristics and molecular markers of UV-Induced Skin Deterioration?
- Study Type Included
- intervention trials
- Condition Being Studied
- The skin with excessive UVR exposure has chemical and biological changes, and these changes have been associated with UV-induced skin deterioration include short-term harmful outcomes such as erythema (sunburn), and long-term consequences such as Photooxidative damage. Photooxidative damage affects cellular lipids, proteins and DNA and it is also involved in the pathobiochemistry of photo-ageing and skin cancer. Therefore, the protection and treatment of skin conditions by daily supplements have received increasing attention.
- Participant
- Participants without severe skin conditions
- Animal
- Human Disease Modelled
- Intervention
- tomato and lycopene
- Comparator Control
- placebo
- Main Outcome
- The baseline and post-intervention indicators of skin health, including indicators of skin erythema, skin molecular markers, symptoms and signs of skin aging. Measures of effect The effect sizes were expressed as Standard Mean Difference (SMD) and 95% Confidence Intervals (95%CI) using fixed- or random-effect models.
- Outcome Measure
- Additional Outcome
- None Measures of effect None
- Study Method
- Systematic review
- Keyword
- Carotenoids; Dietary Supplements; Humans; Lycopene; Lycopersicon esculentum
- Contact
- Jian-Ming Fan [email protected]
- Organisational Affiliation
- Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University
- Funding Source
- This research was financially supported by the National Natural Science Foundation of China (31372453) and Henan Institute of Science and Technology (152102310260).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-05-20
- Registration Date
- 2022-05-30
- Anticipated Start Date
- 2022-01-01
- Anticipated Completion Date
- 2022-06-30
- Title Cn
- 番茄和番茄红素对紫外线诱导皮肤老化的临床特征和分子标志物的影响：干预试验的系统评价与Meta分析
- Title En
- The effect of tomato and lycopene on clinical characteristics and molecular markers of UV-Induced SkinDeterioration: A systematic review and meta-analysis of intervention trials
- Bilingual Status
- complete