Meta AnalysisID 115
不同干预措施预防哺乳期妇女乳头皲裂的疗效：随机对照试验的网状Meta分析
CRD42022313580
To compare the efficacy of different interventions in the prevention of nipple cracking among breastfeeding women in order to better inform clinical practice.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 115
- Evidence Id
- 8673
- Core Evidence Id
- 8673
- Source Meta Analysis Id
- 103
- Herb2 Meta Analysis Id
- HBMA000103
- Crd Id
- CRD42022313580
- Title
- Efficacy of different interventions to prevent nipple cracking among breastfeeding women: a network meta-analysis of randomized controlled trials
- Review Question
- To compare the efficacy of different interventions in the prevention of nipple cracking among breastfeeding women in order to better inform clinical practice.
- Study Type Included
- Randomized controlled trial only and studies using a uniform tool (Nipple Trauma Score) for the assessment of nipple cracking. Quasi-randomized trials will be excluded. Only randomized trials that are peer-reviewed and available in full-text will be eligible for the present systematic review.
- Condition Being Studied
- Breastfeeding has significant benefits for both mother and baby, and the WHO recommends exclusive breastfeeding until six months postpartum. Nipple cracking is a common complication in the first week postpartum, occurring between 29% and 76%, and can reduce breastfeeding satisfaction and even terminate breastfeeding. In addition, cracked nipples can cause bacteria to invade and multiply along the lymphatic vessels through the broken skin, which is the main cause of acute mastitis. Mothers should be educated early in the postpartum period to take measures to prevent the occurrence of cracked nipples to promote successful breastfeeding.
- Participant
- The inclusion criteria included the followings:1) postpartum women who is willing to participate; 2) exclusive breastfeeding; and 3) not using any ointments, oils, and or medications to the nipples. The exclusion criteria included the followings: 1) infants suffering from oral infections，tongue and tooth disorders; 2) using pacifiers, bottles, and plastic nipples for infants; 3) history of maternal psychological disorders reported by mothers; 4) the mother was diagnosed with abnormal nipple infections such as mastitis, abscesses or fungal infections of the breast; 5) mother or infant suffering from any nipple-irrelevant condition that lead to cessation of breastfeeding; and 6) mothers were allergic to the interventions in the study.
- Animal
- Human Disease Modelled
- Intervention
- We will include the following measures: Extra Virgin Olive Oil (EVOO), highly purified anhydrous (HPA) lanolin, peppermint (Mentha piperita) water, peppermint oil，dexpanthenol creams, mint bag，cabbage leaves , breast milk. We will include only studies in which participants are randomized to the intervention. We anticipate that any participants who meets all inclusion criteria could, in principal, be randomised to receive any of the interventions in the synthesis comparator set (assumption of transitivity).
- Comparator Control
- Each measure included in the list above.
- Main Outcome
- Effectiveness of nipple trauma prevention (as continuous outcome) - Response: Measured by mean and standard deviation at baseline, day 3, day 7, and day 14 according to the Nipple Trauma Scale.
- Outcome Measure
- Additional Outcome
- Effectiveness of nipple pain prevention (as continuous outcome) - Response: Measured by mean and standard deviation at baseline, day 3, day 7, and day 14 according to the Visual Analogue Scale.
- Study Method
- Intervention, Network meta-analysis, Prevention, Systematic review
- Keyword
- Breast Feeding; Female; Humans; Network Meta-Analysis; Nipples; Pain Management; Randomized Controlled Trials as Topic
- Contact
- Caifeng Chen [email protected]
- Organisational Affiliation
- Anhui Medical University
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-03-02
- Registration Date
- 2022-04-02
- Anticipated Start Date
- 2022-03-16
- Anticipated Completion Date
- 2022-12-31
- Title Cn
- 不同干预措施预防哺乳期妇女乳头皲裂的疗效：随机对照试验的网状Meta分析
- Title En
- Efficacy of different interventions to prevent nipple cracking among breastfeeding women: a network meta-analysis of randomized controlled trials
- Bilingual Status
- complete