Clinical TrialID 78

A Castor Bean Solution for Cleaning Dentures

NCT01732744

Prostheses-related Infections

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Record Fields

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Clinical Trial Id
78
Evidence Id
78
Core Evidence Id
78
Source Clinical Trial Id
72
Herb2 Clinical Trial Id
HBCT000072
Nct Id
NCT01732744
Title
A Castor Bean Solution for Cleaning Dentures
Status
Completed
Phase
Study Result
No
Study Condition
Prostheses-related Infections
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Intervention
OTHER: Physiological solution|OTHER: Sodium hypochlorite|OTHER: Alkaline Peroxide|OTHER: Castor bean solution
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Triple
Intervention Purpose
Prevention
Gender
All
Age
Adult, Older_Adult
Enrollment
50
Outcome Measure
Denture area covered with biofilm, The volunteers were instructed to brush their dentures ,3 times a day and use the following chemical immersion methods, only once a day after dinner: A)Physiological solution .B) 1% Sodium Hypochlorite .C) Polident Alkaline Peroxide .D) 2,0% Castor bean solution . All the volunteers used one of the four chemical methods in a random sequence for a period of 07 days each. Between each period of use, there was a one week wash out period during which the patient performed his/her habitual cleaning procedure.On the first day and after 07 days of using the interventions, the internal surfaces of dentures were revealed with 1% neutral red solution and photographed with a digital photographic camera. Biofilm was measured on the photographic images of the complete dentures, using the computerized quantitative method "ImageTool". After concluding measurements of the areas (total and biofilm), the percentage of surface covered by biofilm of the complete denture was calculated ., 8 weeks
Sponsor Collaborator
University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo
Funded By
OTHER
Location
Other Id
FORP_491
Start Date
2008-03
Primary Completion Date
2010-11
Completion Date
2011-05
First Posted
2012-11-26
Results First Posted
Last Update Posted
2012-11-26
Study Document
Study Url
https://clinicaltrials.gov/study/NCT01732744
Title Cn
Title En
A Castor Bean Solution for Cleaning Dentures
Bilingual Status
semi_complete