Meta AnalysisID 937
肾上腺素对院外心脏骤停自主循环恢复的影响：试验序贯分析系统评价与Meta分析
CRD42018111763
Does prehospital adrenaline intervention increase return of spontaneous circulation than placebo in out-of-hospital cardiac arrest? Does prehospital adrenaline intervention increase survival to hospital discharge than pl
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Record Fields
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- Meta Analysis Id
- 937
- Evidence Id
- 9495
- Core Evidence Id
- 9495
- Source Meta Analysis Id
- 910
- Herb2 Meta Analysis Id
- HBMA000910
- Crd Id
- CRD42018111763
- Title
- The effect of adrenaline in return of spontaneous circulation in out-of-hospital cardiac arrest: a systematic review and meta-analysis with trial sequential analysis
- Review Question
- Does prehospital adrenaline intervention increase return of spontaneous circulation than placebo in out-of-hospital cardiac arrest? Does prehospital adrenaline intervention increase survival to hospital discharge than placebo in out-of-hospital cardiac arrest? Does prehospital adrenaline intervention increase long term survival than placebo in out-of-hospital cardiac arrest? Does prehospital adrenaline intervention increase neurological adverse events than placebo in out-of-hospital cardiac arrest?
- Study Type Included
- Inclusion: Parallel-arm Clinical trials Systematic reviews/ meta-analysis. Exclusion: Observational studies Case report Case series Reviews (non-systematic) Non-human study.
- Condition Being Studied
- Out-of-hospital cardiac arrest.
- Participant
- Inclusion: adult patients with out-of-hospital cardiac arrest. Exclusion: patients < 18 years old.
- Animal
- Human Disease Modelled
- Intervention
- Prehospital adrenaline (intravenous or intraosseous).
- Comparator Control
- Placebo or no treatment only.
- Main Outcome
- Return of spontaneous circulation, survival to hospital discharge.
- Outcome Measure
- Additional Outcome
- Long term survival, neurological adverse events.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Cardiopulmonary Resuscitation; Epinephrine; Humans; Out-of-Hospital Cardiac Arrest; Physiological Phenomena; Vasoconstrictor Agents
- Contact
- Ka Ting Ng [email protected]
- Organisational Affiliation
- University of Malaya, Department of Anaesthesiology, Faculty of Medicine www.um.edu.my
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England, Malaysia
- Review Stage
- Review Ongoing
- First Submission Date
- 2018-10-05
- Registration Date
- 2018-10-18
- Anticipated Start Date
- 2018-10-08
- Anticipated Completion Date
- 2018-11-01
- Title Cn
- 肾上腺素对院外心脏骤停自主循环恢复的影响：试验序贯分析系统评价与Meta分析
- Title En
- The effect of adrenaline in return of spontaneous circulation in out-of-hospital cardiac arrest: a systematic review and meta-analysis with trial sequential analysis
- Bilingual Status
- complete