Meta AnalysisID 931
木糖醇牙膏预防龋齿的效果：系统评价
CRD42018117424
Does the use of xylitol toothpaste prevent dental caries by reducing caries increment or controlling plaque bacteria?
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Record Fields
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- Meta Analysis Id
- 931
- Evidence Id
- 9489
- Core Evidence Id
- 9489
- Source Meta Analysis Id
- 905
- Herb2 Meta Analysis Id
- HBMA000905
- Crd Id
- CRD42018117424
- Title
- Xylitol toothpaste effect on preventing dental caries: a systematic review
- Review Question
- Does the use of xylitol toothpaste prevent dental caries by reducing caries increment or controlling plaque bacteria?
- Study Type Included
- Randomized or controlled clinical trial
- Condition Being Studied
- Dental caries is the most widespread oral disease worldwide. The disease is the tenth most prevalent condition in children and affects 35% of all ages combined. Untreated dental caries may lead to pain and tooth loss. Untreated dental caries in primary dentition affects 9% of the global population. Xylitol shows prohibitive effect on the growth of streptococci mutans (MS). Its effect on the cariogenic bacteria could have a role in preventing dental caries. The effectiveness of xylitol toothpaste on preventing dental caries is not clearly confirmed. There is no clear agreement on the amount of xylitol in toothpaste for caries prevention. The study aims to evaluate the available evidence on the effectiveness of xylitol toothpaste in prevention of dental caries, in terms of reducing dental caries increment and MS level in plaque or saliva.IN
- Participant
- Inclusion criteria were as follow: Randomized or controlled clinical trial involving human subjects of all age. Studies evaluating the effect of xylitol-containing toothpaste for dental caries prevention. Studies that provided original data generated by means of a comparative trial design.
- Animal
- Human Disease Modelled
- Intervention
- Only using xylitol-containing toothpaste to brush teeth
- Comparator Control
- Only using other non-xylitol toothpaste or placebo toothpaste to brush teeth
- Main Outcome
- Dental caries increments in terms of the decayed, missing, filled surfaces/teeth indexes, S. mutans level in plaque or saliva. Measures of effect Time for dental caries increments should be at least one year study period. Time for S. mutans level should be at least one month study period.
- Outcome Measure
- Additional Outcome
- Study Method
- Systematic review
- Keyword
- Dental Caries; Humans; Toothpastes; Xylitol
- Contact
- Weijia Luo [email protected]
- Organisational Affiliation
- The University of Hong Kong
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Hong Kong
- Review Stage
- Review Completed not published
- First Submission Date
- 2018-11-21
- Registration Date
- 2018-12-12
- Anticipated Start Date
- 2021-07-01
- Anticipated Completion Date
- 2022-12-31
- Title Cn
- 木糖醇牙膏预防龋齿的效果：系统评价
- Title En
- Xylitol toothpaste effect on preventing dental caries: a systematic review
- Bilingual Status
- complete