Meta AnalysisID 917
腺苷脱氨酶诊断腹腔结核的准确性：系统评价与Meta分析
CRD42022297931
To investigate the diagnostic utility of adenosine deaminase for the diagnosis of abdominal tuberculosis. Could adenosine deaminase be used as a diagnostic tool for abdominal tuberculosis?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 917
- Evidence Id
- 9475
- Core Evidence Id
- 9475
- Source Meta Analysis Id
- 889
- Herb2 Meta Analysis Id
- HBMA000889
- Crd Id
- CRD42022297931
- Title
- The diagnostic accuracy of adenosine deaminase for abdominal tuberculosis: a systematic review and meta-analysis
- Review Question
- To investigate the diagnostic utility of adenosine deaminase for the diagnosis of abdominal tuberculosis. Could adenosine deaminase be used as a diagnostic tool for abdominal tuberculosis?
- Study Type Included
- Randomized controlled trials, cross-sectional studies, cohort studies and case controls could be included.
- Condition Being Studied
- Abdominal tuberculosis is one of the most easily involved external pulmonary sites. Tuberculosis is spread by blood, swallowing sputum or spreading to adjacent organs and involving the abdomen. However, it is inefficient to diagnose diseases through microbial evidence. Therefore, it is of great significance to seek a simple, quick and economical biochemical test to achieve the purpose of clinical diagnosis with high specificity and sensitivity.
- Participant
- Inclusion: patients undergoing evaluation for peritoneal effusion Exclusion: animal experiments, case reports, case series, reviews, anonymous reports, editorials or author commentaries.
- Animal
- Human Disease Modelled
- Intervention
- Measurement of peritoneal effusion adenosine deaminase level
- Comparator Control
- Patients with non-tuberculous effusions (e.g. malignant) will be compared
- Main Outcome
- Studies assessing peritoneal effusion adenosine deaminase level in tuberculous and non-tuberculous effusions and providing data on pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of adenosine deaminase.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adenosine Deaminase; Humans; ROC Curve; Sensitivity and Specificity; Tuberculosis
- Contact
- Ruixi Zhou [email protected]
- Organisational Affiliation
- West China Second University Hospital, Sichuan University
- Funding Source
- This work was supported by the National Natural Science Foundation of China (81630038, 81771634, 81842011, 81801629, 81971433, 81971428, 82071353)；the National Key Research and Development Program (2017YFA0104200, 2017YFA0104201)；the grants from the Science and Technology Bureau of Sichuan Province (2021YJ0017, 2020YFS0041)；the Fundamental Research Funds for the Central University (SCU2020D006)；National Key Project of Neonatal Children (1311200003303)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-12-13
- Registration Date
- 2022-01-13
- Anticipated Start Date
- 2021-12-01
- Anticipated Completion Date
- 2022-03-31
- Title Cn
- 腺苷脱氨酶诊断腹腔结核的准确性：系统评价与Meta分析
- Title En
- The diagnostic accuracy of adenosine deaminase for abdominal tuberculosis: a systematic review and meta-analysis
- Bilingual Status
- complete