Meta AnalysisID 914
单注射器与双注射器腺苷给药技术治疗室上性心动过速的系统评价与Meta分析
CRD42022345125
Is the single-syringe technique of adenosine administration more effective than the double-syringe technique for terminating supraventricular tachycardia?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 914
- Evidence Id
- 9472
- Core Evidence Id
- 9472
- Source Meta Analysis Id
- 887
- Herb2 Meta Analysis Id
- HBMA000887
- Crd Id
- CRD42022345125
- Title
- The single-syringe versus the double-syringe techniques of adenosine administration for supraventricular tachycardia: a systematic review and meta-analysis
- Review Question
- Is the single-syringe technique of adenosine administration more effective than the double-syringe technique for terminating supraventricular tachycardia?
- Study Type Included
- Randomized controlled trials and observational studies will be included
- Condition Being Studied
- Given the physical logistic issues and inconvenience of the typical double-syringe adenosine administration for supraventricular tachycardia termination, an alternative method of combining adenosine and normal saline solution flush in a single-syringe administration has been proposed. Although several studies have already tested the feasibility, termination rate, and total administered dose as outcomes of this new method on supraventricular tachycardia patients, there is no meta-analysis on this topic yet, and a definitive assessment of these endpoints is still unclear. Therefore, we aim to perform a systematic review and meta-analysis examining the feasibility and efficacy of single-syringe adenosine administration in patients with supraventricular tachycardia, specifically interested in end-points such as termination rate, total administered dose, and adverse effects.
- Participant
- We will include randomized controlled trials (RCTs) and observational studies comparing the use of single-syringe with double-syringe techniques of adenosine administration in all patients diagnosed with supraventricular tachycardia, reporting the clinical outcomes of interest. We will exclude studies with overlapping patient populations.
- Animal
- Human Disease Modelled
- Intervention
- The single-syringe technique of adenosine administration
- Comparator Control
- The double-syringe technique of adenosine administration
- Main Outcome
- We will extract data for a pooled analysis on the following outcomes: (1) termination rate, (2) termination rate at first dose, (3) total administered dose, (4) adverse effects, and (5) discharge rate. Measures of effect Risk or odds ratio
- Outcome Measure
- Additional Outcome
- Termination rate, termination rate at first dose, total administered dose, adverse effects, and discharge rate. Measures of effect Risk or odds ratio
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Adenosine; Anti-Arrhythmia Agents; Humans; Syringes; Tachycardia, Supraventricular
- Contact
- Isabele Ayumi Miyawaki [email protected]
- Organisational Affiliation
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- United States of America
- Review Stage
- Review Completed not published
- First Submission Date
- 2022-07-08
- Registration Date
- 2022-07-18
- Anticipated Start Date
- 2022-07-10
- Anticipated Completion Date
- 2022-08-20
- Title Cn
- 单注射器与双注射器腺苷给药技术治疗室上性心动过速的系统评价与Meta分析
- Title En
- The single-syringe versus the double-syringe techniques of adenosine administration for supraventricular tachycardia: a systematic review and meta-analysis
- Bilingual Status
- complete