Meta AnalysisID 894
醋酸肉眼观察与初级HPV检测和/或巴氏涂片检查效果比较的系统评价
CRD42020206154
What is the effectiveness of visual inspection with acetic acid (VIA) as compared to primary HPV testing and/or pap smear (standard) among non-pregnant women aged 30-65 in low- and middle-income countries?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 894
- Evidence Id
- 9452
- Core Evidence Id
- 9452
- Source Meta Analysis Id
- 869
- Herb2 Meta Analysis Id
- HBMA000869
- Crd Id
- CRD42020206154
- Title
- Systematic Review Evaluating the Effectiveness of Visual Inspection with Acetic Acid (VIA) as Compared to Primary HPV Testing and/or Pap Smear
- Review Question
- What is the effectiveness of visual inspection with acetic acid (VIA) as compared to primary HPV testing and/or pap smear (standard) among non-pregnant women aged 30-65 in low- and middle-income countries?
- Study Type Included
- Inclusion Criteria: • Other systematic reviews • Randomized trials • Other experimental studies • Observational (e.g., cohort, cross-sectional, case-control) Exclusion Criteria: • Qualitative • Case studies • Case series
- Condition Being Studied
- This systematic review will focus on screening outcomes of Visual Inspection with Acetic Acid compared to Primary HPV Testing and Pap smear (gold standard). These screening methods lead to additional screening and diagnoses related to HPV and cervical cancer.
- Participant
- Inclusion Criteria: Non-pregnant women aged 30-65 in low- and middle-income countries who received Visual Inspection with Acetic Acid (VIA) Testing, Primary HPV Testing or Pap smear. Exclusion Criteria: Pregnant women, women aged < 30, women aged > 65
- Animal
- Human Disease Modelled
- Intervention
- Inclusion Criteria: Visual Inspection with Acetic Acid (VIA), Primary HPV Testing, Pap smear (Gold Standard) Exclusion Criteria: Co-HPV Testing, Reflex HPV Testing, Diagnostic Testing
- Comparator Control
- Inclusion Criteria: • VIA compared to pap smear • Primary HPV testing compared to pap smear • VIA compared to primary HPV testing • Include studies comparing Visual Inspection with Lugol’s Iodine to any previously listed comparators *Pap smear as gold standard Exclusion Criteria: Co-HPV Testing, Reflex HPV Testing, Diagnostic Testing
- Main Outcome
- Inclusion criteria: • Sensitivity • Specificity • Prevalence • Positive predictive value • Negative predictive value • Adverse Outcomes • Yield • Likelihood ratio • Clinical Outcomes: Normal, Normal with HPV, Ascus, L-sil (Low Grade) and H-sil (High Grade) Exclusion criteria: • Crude numbers (e.g., not a rate or ratio) Measures of effect ORs, NNT, PPV, sensitivity, specificity, NPV, yield, estimates of prediction (brier scores, AUC)
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not applicable
- Study Method
- Prevention, Prospective meta-analysis (PMA), Systematic review
- Keyword
- Acetates; Female; Humans; Papanicolaou Test; Papillomavirus Infections; Uterine Cervical Neoplasms; Vaginal Smears
- Contact
- Sabrina Smith [email protected]
- Organisational Affiliation
- Emory University - Rollins School of Public Health https://www.sph.emory.edu/
- Funding Source
- Emory University - Rollins School of Public Health is sponsoring this review through provision of personnel and resources. Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> N/A
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- United States of America
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-11-05
- Registration Date
- 2020-12-06
- Anticipated Start Date
- 2020-04-01
- Anticipated Completion Date
- 2021-04-30
- Title Cn
- 醋酸肉眼观察与初级HPV检测和/或巴氏涂片检查效果比较的系统评价
- Title En
- Systematic Review Evaluating the Effectiveness of Visual Inspection with Acetic Acid (VIA) as Compared to Primary HPV Testing and/or Pap Smear
- Bilingual Status
- complete