Meta AnalysisID 890

成年人膳食醋酸摄入对血清葡萄糖和血脂谱的生理效应:一项系统评价

CRD42018094178

To investigate the physiological effects of dietary acetic acid (acetate) consumption in human adults on serum glucose and lipid profiles. PICO: P (Population): human adults; I (Intervention): dietary intake of acetic ac

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Record Fields

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Meta Analysis Id
890
Evidence Id
9448
Core Evidence Id
9448
Source Meta Analysis Id
865
Herb2 Meta Analysis Id
HBMA000865
Crd Id
CRD42018094178
Title
The physiological effects of dietary acetic acid (acetate) consumption in human adults on serum glucose and lipid profiles: a systematic review
Review Question
To investigate the physiological effects of dietary acetic acid (acetate) consumption in human adults on serum glucose and lipid profiles. PICO: P (Population): human adults; I (Intervention): dietary intake of acetic acid (no intravenous or pharmaceutical (i.e. in pill form) administration); C (Comparator): placebo, no intervention, alternative intervention (e.g. apple cider vinegar compared to apple juice); O (Outcome): serum lipid and glucose profiles.
Study Type Included
Included: cohort studies, pilot studies, cross-over studies and randomised trials. Excluded: case control studies, cross-sectional studies, screening studies and prevention trials.
Condition Being Studied
Therapeutic and adverse cardiometabolic outcomes as a consequence of dietary acetic acid consumption.
Participant
Inclusion: all human adults (18-65 years of age), regardless of health status, residency or ethnicity.  Exclusion: children and the elderly.
Animal
Human Disease Modelled
Intervention
Inclusion: intake of a dietary form of acetic acid. This predominately includes vinegar (apple cider, white, red, wine), kombucha and kimchi.  Exclusion: intravenous of pharmacological forms of acetic acid delivery (i.e. in a tablet or pill form).
Comparator Control
Placebo, no intervention, or another intervention without acetic acid (e.g. comparing apple cider vinegar intake to apple juice intake).
Main Outcome
Lipid and blood glucose profiles associated with the consumption of acetic acid in the diet. Measures of effect Fasting blood glucose, insulin sensitivity and serum lipoprotein ratios.
Outcome Measure
Additional Outcome
Dosages utilised, and anthropometric changes following intake. Measures of effect Not applicable.
Study Method
Intervention, Systematic review
Keyword
Acetates; Acetic Acid; Adult; Blood Glucose; Cardiovascular System; Diet; Glucose; Humans; Insulin Resistance; Lipids; Lipoproteins; Metabolism; Serum
Contact
Daniela Valdes [email protected]
Organisational Affiliation
Monash University Gastroenterology Department https://www.monash.edu/medicinehttps://www.monash.edu/medicine/ccs/gastroenterology/staffccs/gastroenterology/staff
Funding Source
Other Selection Criteria
Final Publication
Valdes, D. S., So, D., Gill, P. A., & Kellow, N. J. (2021). Effect of Dietary Acetic Acid Supplementation on Plasma Glucose, Lipid Profiles, and Body Mass Index in Human Adults: A Systematic Review and Meta-analysis. Journal of the Academy of Nutrition and Dietetics, 121(5), 895–914. https://doi.org/10.1016/j.jand.2020.12.002 PMID:
Same Topic Review
Published Protocol
Review Type
Language
Country
Australia
Review Stage
Review Completed published
First Submission Date
2018-04-18
Registration Date
2018-05-01
Anticipated Start Date
2018-04-23
Anticipated Completion Date
2019-01-10
Title Cn
成年人膳食醋酸摄入对血清葡萄糖和血脂谱的生理效应:一项系统评价
Title En
The physiological effects of dietary acetic acid (acetate) consumption in human adults on serum glucose and lipid profiles: a systematic review
Bilingual Status
complete