Meta AnalysisID 871

氢化可的松治疗脓毒性心肌病的系统评价与Meta分析

CRD42022357855

The aim of this meta-analysis is to evaluate the efficacy and safety of hydrocortisone on Septic Cardiomyopathy

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Record Fields

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Meta Analysis Id
871
Evidence Id
9429
Core Evidence Id
9429
Source Meta Analysis Id
844
Herb2 Meta Analysis Id
HBMA000844
Crd Id
CRD42022357855
Title
A systematic review and meta-analysis of hydrocortisone in Septic Cardiomyopathy
Review Question
The aim of this meta-analysis is to evaluate the efficacy and safety of hydrocortisone on Septic Cardiomyopathy
Study Type Included
Randomized controlled trials and observational studies
Condition Being Studied
Sepsis is a dysregulated host response to infection that involves various organs and septic cardiomyopathy is one manifestation of septic shock and is associated with a mortality rate of up to 50%.the main goal is to assess the role of hydrocortisone on Septic Cardiomyopathy.
Participant
patients with Septic Cardiomyopathy will be included
Animal
Human Disease Modelled
Intervention
hydrocortisone was the main intervention
Comparator Control
non-hydrocortisone as control group
Main Outcome
all-cause mortality, proportion of patients with one or more serious adverse events Measures of effect RR/OR SMD/MD HR
Outcome Measure
Additional Outcome
incidence of acute kidney injury duration of MV, duration of vasopressor or inotropic therapy, vasopressor-free days, transfusion with any form of blood, product, ICU length of stay (LOS), and hospital LOS
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Cardiomyopathies; Hospital Mortality; Humans; Hydrocortisone; Shock, Septic
Contact
shenhui Jin [email protected]
Organisational Affiliation
the first hospital of wenzhou medical university
Funding Source
no funding
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-09-03
Registration Date
2022-09-14
Anticipated Start Date
2022-09-15
Anticipated Completion Date
2023-08-31
Title Cn
氢化可的松治疗脓毒性心肌病的系统评价与Meta分析
Title En
A systematic review and meta-analysis of hydrocortisone in Septic Cardiomyopathy
Bilingual Status
complete