Meta AnalysisID 83
穴位刺激对恶性肿瘤患者外周血T淋巴细胞亚群及NK细胞的影响
CRD42020167842
Patients: patients diagnosed with malignant tumor Intervention: acupoint stimulation eg.acupuncture, moxibustion, warming needle Control: routine treatment, sham acupuncture, sham acupoint stimulation Outcome: T cell sub
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Record Fields
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- Meta Analysis Id
- 83
- Evidence Id
- 8641
- Core Evidence Id
- 8641
- Source Meta Analysis Id
- 76
- Herb2 Meta Analysis Id
- HBMA000076
- Crd Id
- CRD42020167842
- Title
- The Effects of Acupoint Stimulation on T Lymphocyte Subgroups and NK Cell in Peripheral Blood of Patients with Malignant Tumor
- Review Question
- Patients: patients diagnosed with malignant tumor Intervention: acupoint stimulation eg.acupuncture, moxibustion, warming needle Control: routine treatment, sham acupuncture, sham acupoint stimulation Outcome: T cell subgroup(CD3+, CD4+, CD8+, etc), NK cell Study design: RCTs
- Study Type Included
- Inclusion： (1)Adults diagnosed with malignant tumor. (2)Acupoint stimulation (eg. acupuncture, moxibustion, acupoint injection, TEAS) was the primary intervention in the experiment group; (3) Sham and/or blank control procedure was performed; (4) Primary outcomes included T cell subgroup percentage and NK cell percentage in peripheral blood; (5) Studies that had a randomized controlled trial (RCT) design; Exclusion: 1) RCTs which compare one acupoint stimulation method with another traditional medical method 2) the evaluation criteria do not include standardized outcome indicators;
- Condition Being Studied
- malignant tumor, immune system
- Participant
- Inclusion: Adults with malignant tumor. Exclusion: Adolescents (under 15 years of age) .
- Animal
- Human Disease Modelled
- Intervention
- Acupuncture is considered a complementary or alternative medicine in many Asian countries as well as in the west. Moxibustion is a traditional Chinese medicine treatment that involves burning dried mugwort at specific parts of the body.Suppliers usually age the mugwort and grind it into fluff.Practitioners burn the fuzz or further process it into cigar-shaped sticks. They can use it indirectly, with acupuncture needles, or burn it on the patient's skin. Acupuncture is a form of alternative medicine and an important part of the traditional Chinese medicine (TCM) used to insert fine needles into the body.It is most often used to relieve pain, but can also be used for a variety of other symptoms.
- Comparator Control
- Routine Treatment: treatment according to symptoms; Sham Transcutaneous Electrical Acupoint Stimulation: electrode tabs are placed on the acupoints, but electrical stimulation is not initiated.
- Main Outcome
- Peripheral blood NKcell, Tcell subgroup：CD4 +，CD8 +，CD3 + cell； CD4 + / CD8 + by flow cytometry. Measures of effect Timing：before and after the course of treatment. Measures: the change of percentage of T cell subgroups and NK cell in peripheral blood.
- Outcome Measure
- Additional Outcome
- none Measures of effect none
- Study Method
- 系统评价
- Keyword
- Humans
- Contact
- Tianqi Chen [email protected]
- Organisational Affiliation
- the first teaching hospital of tianjin university of TCM http://www.tjtcm.cn/
- Funding Source
- Tianjin Science & Technology Plan Projects (No. 17ZXMFSY00190), Tianjin Traditional Chinese Medicine Research Project, Tianjin health and family planning commission [No. 2017003] and the National Natural Science Foundation of China [No. 81403220].
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-02-04
- Registration Date
- 2020-04-28
- Anticipated Start Date
- 2020-02-20
- Anticipated Completion Date
- 2020-04-30
- Title Cn
- 穴位刺激对恶性肿瘤患者外周血T淋巴细胞亚群及NK细胞的影响
- Title En
- The Effects of Acupoint Stimulation on T Lymphocyte Subgroups and NK Cell in Peripheral Blood of Patients with Malignant Tumor
- Bilingual Status
- complete