Meta AnalysisID 826

氯己定和毛果芸香碱在电离辐射暴露的口腔黏膜上皮中的应用

CRD42022362181

How does the use of Chlorhexidine and Pilocarpine affect oral mucosal epithelium which is exposed by ionizing radiation?

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Record Fields

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Meta Analysis Id
826
Evidence Id
9384
Core Evidence Id
9384
Source Meta Analysis Id
798
Herb2 Meta Analysis Id
HBMA000798
Crd Id
CRD42022362181
Title
The use of chlorhexidine and pilocarpine for oral mucosal epithelium, exposed to ionizing radiation.
Review Question
How does the use of Chlorhexidine and Pilocarpine affect oral mucosal epithelium which is exposed by ionizing radiation?
Study Type Included
There are no restrictions on the types of study designs.
Condition Being Studied
Oral mucositis and xerostomia.
Participant
People of all age range who are affected by ionizing radiation and experience symptoms of oral mucositis or/and xerostomia.
Animal
Human Disease Modelled
Intervention
The use of ionizing radiation plays a severe role in medical practice. It affects people's oral health by causing oral mucositis and/or xerostomia. It is important to search for the best possible treatment of these pathologies. In clinical practice the most commonly used medications are Chlorhexidine and Pilocarpine. Therefore it is vital to compare them, in order to analyze their effect and to find out the best solution for each condition.
Comparator Control
Not applicable
Main Outcome
The main aim is to find out how does the use of Chlorhexidine and Pilocarpine affect oral mucosal epithelium which is exposed by ionizing radiation and present clinical recommendations.
Outcome Measure
Additional Outcome
None.
Study Method
Systematic review
Keyword
Chlorhexidine; Epithelium; Humans; Mouth Mucosa; Pilocarpine; Radiation, Ionizing
Contact
Simona Plusciauskaite [email protected]
Organisational Affiliation
Lithuanian University of Health Sciences https://lsmuni.lt/en/
Funding Source
Managing by Assistant/associate professor Justina Stucinskaite-Maracinskiene
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English, Lithuanian
Country
Lithuania
Review Stage
Review Ongoing
First Submission Date
2022-09-22
Registration Date
2022-10-03
Anticipated Start Date
2022-10-06
Anticipated Completion Date
2023-06-30
Title Cn
氯己定和毛果芸香碱在电离辐射暴露的口腔黏膜上皮中的应用
Title En
The use of chlorhexidine and pilocarpine for oral mucosal epithelium, exposed to ionizing radiation.
Bilingual Status
complete