Meta AnalysisID 8017
咖啡酸片治疗血小板减少症的疗效与安全性：系统评价与Meta分析
CRD42023408324
P:The included study cases were all patients with a diagnosis of thrombocytopenia. I:Intervention measures: Patients in the test group were treated with caffeic acid tablets (200-300 mg/time, 3 times/d. Dezhou Deyao Phar
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 8017
- Evidence Id
- 16575
- Core Evidence Id
- 16575
- Source Meta Analysis Id
- 8017
- Herb2 Meta Analysis Id
- HBMA008017
- Crd Id
- CRD42023408324
- Title
- Efficacy and safety of caffeic acid tablets in the treatment of thrombocytopenia: a systematic review and meta-analysis
- Review Question
- P:The included study cases were all patients with a diagnosis of thrombocytopenia. I:Intervention measures: Patients in the test group were treated with caffeic acid tablets (200-300 mg/time, 3 times/d. Dezhou Deyao Pharmaceutical Co., Ltd., approved by Chinese medicine H37020537, production batch number: 2102140503.) C:conventional drugs (hormonal drugs, recombinant human granulocyte-stimulating factor and other platelet-raising drugs), and the dose and duration of administration were not limited. O:The primary indicators were platelet count changes and clinical efficacy (complete remission: platelet count ≥100×109/L; partial remission: 50×109/L < platelet count <100×109/L; ineffective: platelet count ≤50×109/L, clinical efficacy = complete remission + partial remission). Secondary indicators were incidence of adverse reactions, bone marrow suppression, change in white blood cell count, change in neutrophil count, and change in hemoglobin.
- Study Type Included
- Only randomized controlled trials (RCT) were included and the languages were limited to Chinese and English.
- Condition Being Studied
- Thrombocytopenias
- Participant
- P:The included study cases were all patients with a diagnosis of thrombocytopenia.
- Animal
- Human Disease Modelled
- Intervention
- I:Intervention measures: Patients in the test group were treated with caffeic acid tablets (200-300 mg/time, 3 times/d. Dezhou Deyao Pharmaceutical Co., Ltd., approved by Chinese medicine H37020537, production batch number: 2102140503.)
- Comparator Control
- C:conventional drugs (hormonal drugs, recombinant human granulocyte-stimulating factor and other platelet-raising drugs), and the dose and duration of administration were not limited.
- Main Outcome
- O:The primary indicators were platelet count changes and clinical efficacy (complete remission: platelet count ≥100×109/L; partial remission: 50×109/L < platelet count <100×109/L; ineffective: platelet count ≤50×109/L, clinical efficacy = complete remission + partial remission). Secondary indicators were incidence of adverse reactions, bone marrow suppression, change in white blood cell count, change in neutrophil count, and change in hemoglobin.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Hemoglobins; Humans; Incidence; Leukocyte Count; Leukopenia; Neutrophils; Tablets; Thrombocytopenia; caffeic acid
- Contact
- Hongxiu Yu [email protected]
- Organisational Affiliation
- Dali University
- Funding Source
- This research was funded by the Major Projects of Science and Technology Plan of Dali state (No. D2019NA03) and LJ Expert Workstation of Yunnan Province (No. 202005AF150013).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-03-15
- Registration Date
- 2023-03-26
- Anticipated Start Date
- 2023-02-02
- Anticipated Completion Date
- 2023-04-20
- Title Cn
- 咖啡酸片治疗血小板减少症的疗效与安全性：系统评价与Meta分析
- Title En
- Efficacy and safety of caffeic acid tablets in the treatment of thrombocytopenia: a systematic review and meta-analysis
- Bilingual Status
- complete