Meta AnalysisID 8014
非药物干预对新生儿重症监护室早产儿疼痛的影响——随机对照试验的网状Meta分析
CRD42023412200
1 Effects of non-pharmacological interventions on pain in preterm infants in the neonatal intensive care unit. (Tactile relief, auditory intervention, olfactory stimulation, combined oral sucrose and non-nutritive suckin
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 8014
- Evidence Id
- 16572
- Core Evidence Id
- 16572
- Source Meta Analysis Id
- 8013
- Herb2 Meta Analysis Id
- HBMA008013
- Crd Id
- CRD42023412200
- Title
- Effect of non-pharmacological interventions on pain in preterm infants in the neonatal intensive care unit—a network meta-analysis of randomized controlled trials
- Review Question
- 1 Effects of non-pharmacological interventions on pain in preterm infants in the neonatal intensive care unit. (Tactile relief, auditory intervention, olfactory stimulation, combined oral sucrose and non-nutritive sucking, facilitated tucking, and mixed intervention) 2 Which non-pharmacological intervention has the best analgesic effect?
- Study Type Included
- Inclusion criteria: Randomized controlled trials. Exclusion criteria: 1 Results of pain score, oxygen saturation and heart rate were ambiguous or missing. 2 Non-RCTs, non-English literature, non-human studies, repeated publications, case studies, reviews, and meta-analyses were excluded.
- Condition Being Studied
- Preterm infants with procedural pain in the neonatal intensive care unit.
- Participant
- Inclusion criteria: 1 Preterm infants in the neonatal intensive care unit. 2 Gestational age < 37 weeks. Exclusion criteria: 1 Full-term infants or other non-preterm infants.
- Animal
- Human Disease Modelled
- Intervention
- Preterm infants in the neonatal intensive care unit are exposed to numerous painful procedures such as tracheal intubation, tracheal aspiration, venipuncture, ect. Because repeated and persistent pain may have an impact on neurological and behavior-oriented development in preterm infants, maximum attention needs to be given to pain management in preterm infants. Pain relief is increasingly being discussed in non-phramacological interventions, such as tactile relief, auditory intervention, olfactory stimulation, combined oral sucrose and non-nutritive sucking, facilitated tucking, and mixed intervention. We will collect data from randomized controlled trials that the application of non-phramacological interventions to painful preterm infants in the neonatal intensive care unit. Non-phramacological interventions：①Tactile relief（Kangaroo mother care, gentle human touch, massage）②Auditory intervention（mothers' voice, white noise, lullaby）③Olfactory stimulation（maternal breast milk odor, vanilla odor, amniotic fluid odor）④Combined oral sucrose and non-nutritive sucking（OS+NNS) ⑤Facilitated tucking⑥Mixed intervention
- Comparator Control
- We will include studies that use routine nursing care, including placebo, pacifier, and incubator. Exclusion criteria: The control group included medication or several other interventions.
- Main Outcome
- pain score(PIPP) Measures of effect SMD, OR, and 95%CI. Information for pain scale from RCT papers.
- Outcome Measure
- Additional Outcome
- heart rate, oxygen saturation Measures of effect SMD, OR, and 95%CI. Information from RCT papers.
- Study Method
- Network meta-analysis, Systematic review
- Keyword
- Humans
- Contact
- Zhifang Chen [email protected]
- Organisational Affiliation
- Affiliated Maternity and Child Health Care Hospital of Nantong University https://www.ntfybj.com
- Funding Source
- Project name：Evaluation of early sucking assessment technique and feeding outcome of newborns in labor analgesic women Item number：MS12021040 Reporting unit：Affiliated Maternity and Child Health Care Hospital of Nantong University Zip：226018 Project leader：Zhifang Chen Competent authorities：Nantong Municipal Health Commission Grant number(s) State the funder, grant or award number and the date of award Item number：MS12021040
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-03-28
- Registration Date
- 2023-04-08
- Anticipated Start Date
- 2023-04-28
- Anticipated Completion Date
- 2023-05-26
- Title Cn
- 非药物干预对新生儿重症监护室早产儿疼痛的影响——随机对照试验的网状Meta分析
- Title En
- Effect of non-pharmacological interventions on pain in preterm infants in the neonatal intensive care unit—a network meta-analysis of randomized controlled trials
- Bilingual Status
- complete