Meta AnalysisID 8010
早产儿视网膜病变筛查中的非药物镇痛干预：系统评价与Meta分析
CRD42023432500
In preterm neonates undergoing ROP screening (Population), are non-pharmacological pain management interventions used alone or in combination with topical anaesthesia (Intervention) compared to placebo or topical analges
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 8010
- Evidence Id
- 16568
- Core Evidence Id
- 16568
- Source Meta Analysis Id
- 8014
- Herb2 Meta Analysis Id
- HBMA008014
- Crd Id
- CRD42023432500
- Title
- Non-pharmacological pain relief interventions in preterm neonates undergoing screening for retinopathy of prematurity:Systematic review and metaanalysis
- Review Question
- In preterm neonates undergoing ROP screening (Population), are non-pharmacological pain management interventions used alone or in combination with topical anaesthesia (Intervention) compared to placebo or topical analgesics (Comparison) efficacious for pain relief assessed by preterm pain scores (Outcome).
- Study Type Included
- RCT with outcome measures including pain scores
- Condition Being Studied
- Retinopathy of prematurity is a potentially blinding condition affecting neonates. routine screening is recommended for early detection and treatment to prevent blindness. The procedure is painful and topical anaesthesia that is currently recommended for pain relief does not completely alleviate pain.
- Participant
- Preterm neonates undergoing retinopathy of prematurity screening
- Animal
- Human Disease Modelled
- Intervention
- Non-pharmacological pain management interventions (Breastmilk, sucrose, glucose, “non-nutritive sucking” swaddling, nesting, kangaroo mother care, “facilitated tucking” touch, “developmental care”, music) used alone or in combination with topical anaesthesia
- Comparator Control
- placebo and or topical anaesthesia
- Main Outcome
- Pain relief or reduction in pain scores Measures of effect Relative risk/ Odds ratio
- Outcome Measure
- Additional Outcome
- Heart rate , Oxygen saturation variability Measures of effect relative risk/ odds ratio
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Analgesics; Anesthesia, Local; Humans; Infant, Newborn; Infant, Premature; Pain Management; Retinopathy of Prematurity
- Contact
- IYABODE OLABISI DEDEKE [email protected]
- Organisational Affiliation
- Federal Medical Centre https://fmcabeokuta.net
- Funding Source
- None Grant number(s) State the funder, grant or award number and the date of award None
- Other Selection Criteria
- Final Publication
- Fajolu IB, Dedeke IOF, Ezenwa BN, Ezeaka VC. Non-pharmacological pain relief interventions in preterm neonates undergoing screening for retinopathy of prematurity: a systematic review. BMJ Open Ophthalmol. 2023 Dec 6;8(1):e001271. doi: 10.1136/bmjophth-2023-001271. PMID: 38057104; PMCID: PMC10711824. https://PubMed.ncbi.nlm.nih.gov/38057104/
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Nigeria
- Review Stage
- Review Completed published
- First Submission Date
- 2023-06-04
- Registration Date
- 2023-06-16
- Anticipated Start Date
- 2023-06-09
- Anticipated Completion Date
- 2023-08-15
- Title Cn
- 早产儿视网膜病变筛查中的非药物镇痛干预：系统评价与Meta分析
- Title En
- Non-pharmacological pain relief interventions in preterm neonates undergoing screening for retinopathy of prematurity:Systematic review and metaanalysis
- Bilingual Status
- complete