Meta AnalysisID 7961
补充维生素K对中老年人群不同部位骨密度和骨代谢的影响：一项随机对照试验的Meta分析与系统评价
CRD42023432432
This meta-analysis and systematic review aimed to investigate the effects of vitamin K supplementation on bone mineral density (BMD) at different sites and bone metabolism in middle-aged and older adults comprehensively.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7961
- Evidence Id
- 16519
- Core Evidence Id
- 16519
- Source Meta Analysis Id
- 7959
- Herb2 Meta Analysis Id
- HBMA007959
- Crd Id
- CRD42023432432
- Title
- Effects of vitamin K supplementation on bone mineral density at different sites and bone metabolism in the middle-aged and elderly population: a meta-analysis of randomized controlled trials and systematic review.
- Review Question
- This meta-analysis and systematic review aimed to investigate the effects of vitamin K supplementation on bone mineral density (BMD) at different sites and bone metabolism in middle-aged and older adults comprehensively.
- Study Type Included
- Study design: randomized controlled trials (RCTs)
- Condition Being Studied
- Bone-related diseases are global public health issues, which include osteoporosis (OP), fracture, osteoarthritis (OA), etc. There are about 20 billion OP and 25.02 billion OA patients worldwide. Osteoporosis causes more than 8.9 million fractures each year. It has been reported that about one in three women and one in five men will occur fracture. Along with the global aging process, the health of middle-aged and elderly adults is getting more and more attention. Prevention and treatment of bone-related diseases play an important role in the quality life of the middle-aged and elderly. Among the treatments, dietary nutrition intervention may be an important method to prevent and treat bone-related diseases.
- Participant
- Inclusion criteria Participants: middle-aged and elderly people Exclusion criteria Special participants, such as athletes
- Animal
- Human Disease Modelled
- Intervention
- Inclusion criteria Intervention: vitamin K supplement of any form and the dosage is clear
- Comparator Control
- Inclusion criteria Control: placebo, calcium, vitamin D or blank control;
- Main Outcome
- BMD (femoral neck BMD, lumbar spine BMD, total hip BMD, Femoral Ward BMD, Ultra distal radius BMD)
- Outcome Measure
- Additional Outcome
- Total osteocalcin (tOC); the undercarboxylated osteocalcin (ucOC); osteocalcin (OC); ucOC to tOC ratio; cOC to ucOC ratio; NTx;
- Study Method
- Systematic review
- Keyword
- Aged; Bone Density; Dietary Supplements; Humans; Middle Aged; Minerals; Randomized Controlled Trials as Topic; Vitamins
- Contact
- gao tianlin [email protected]
- Organisational Affiliation
- School of Public Health, Qingdao University
- Funding Source
- No funding sponsors
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-04
- Registration Date
- 2023-06-16
- Anticipated Start Date
- 2023-03-07
- Anticipated Completion Date
- 2023-07-10
- Title Cn
- 补充维生素K对中老年人群不同部位骨密度和骨代谢的影响：一项随机对照试验的Meta分析与系统评价
- Title En
- Effects of vitamin K supplementation on bone mineral density at different sites and bone metabolism in the middle-aged and elderly population: a meta-analysis of randomized controlled trials and systematic review.
- Bilingual Status
- complete