Meta AnalysisID 7953
B族维生素与冠心病风险：一项系统评价与Meta分析
CRD42023421930
The aims of this study are to fully evaluate whether B vitamins supplementation has a beneficial effect on reducing the risk of coronary heart disease via systematic review and meta-analysis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7953
- Evidence Id
- 16511
- Core Evidence Id
- 16511
- Source Meta Analysis Id
- 7951
- Herb2 Meta Analysis Id
- HBMA007951
- Crd Id
- CRD42023421930
- Title
- B vitamins and risk of coronary heart disease: a systematic review and meta-analysis
- Review Question
- The aims of this study are to fully evaluate whether B vitamins supplementation has a beneficial effect on reducing the risk of coronary heart disease via systematic review and meta-analysis
- Study Type Included
- RCT
- Condition Being Studied
- Coronary heart disease is one of the major cardiovascular diseases threatening human health, with 11 million people suffering from coronary heart disease in China. The early stage of coronary heart disease is usually asymptomatic. Some patients may have symptoms of angina pectoris after strenuous activities. In severe cases, patients may have a sense of chest pressure, shortness of breath, and feel very tired. B vitamins, for their effectiveness in preventing coronary heart disease, have been studied, but the available results are incomplete and contradictory, so the purpose of this systematic review and meta-analysis was to fully assess whether B vitamin supplementation would have a beneficial effect on reducing the risk of coronary heart disease.
- Participant
- Inclusion criteria: Randomized controlled studies, randomized controlled trials included in the analysis were limited to trials with at least 2 patients and at least 6 months of follow-up to ensure that only high quality studies were included, no language restrictions were included, and the outcome indicators were coronary heart disease and its complications. Exclusion criteria: case reports that are not randomized controlled studies, do not belong to the population of the disease, do not meet the size and duration requirements for inclusion, are of low quality and have insufficient outcome indicators, duplicate data, and studies using the same population or overlapping databases and animal models.
- Animal
- Human Disease Modelled
- Intervention
- The experimental population was randomly divided into two groups: the intervention group was given a combination pill containing B vitamins
- Comparator Control
- The subjects were randomly divided into two groups: the control group received a placebo
- Main Outcome
- RR-mortality, morbidity Measures of effect coronary heart disease
- Outcome Measure
- Additional Outcome
- RR-mortality, morbidity Measures of effect Myocardial Infarction
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Coronary Disease; Dietary Supplements; Humans; Vitamin B Complex
- Contact
- Dongdong Yuan [email protected]
- Organisational Affiliation
- The 7th People's Hospital of Zhengzhou
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-04-27
- Registration Date
- 2023-05-08
- Anticipated Start Date
- 2023-04-27
- Anticipated Completion Date
- 2023-05-27
- Title Cn
- B族维生素与冠心病风险：一项系统评价与Meta分析
- Title En
- B vitamins and risk of coronary heart disease: a systematic review and meta-analysis
- Bilingual Status
- complete