Meta AnalysisID 7939
早期使用加压素是否更可能减少脓毒性休克中肾脏替代治疗的使用？一项系统评价与Meta分析
CRD42023490386
Will early use of vasopressin be more likely to reduce the use of RRT in septic shock?
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Record Fields
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- Meta Analysis Id
- 7939
- Evidence Id
- 16497
- Core Evidence Id
- 16497
- Source Meta Analysis Id
- 7935
- Herb2 Meta Analysis Id
- HBMA007935
- Crd Id
- CRD42023490386
- Title
- Will early use of vasopressin be more likely to reduce the use of RRT in septic shock? A systematic review and meta-analysis
- Review Question
- Will early use of vasopressin be more likely to reduce the use of RRT in septic shock?
- Study Type Included
- The inclusion criteria were as follows: (1) adult patients (> 16 years) with septic shock, septic shock was classified according to the current Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis3.0); (2) RCTs as well as prospective and retrospective cohort studies;(3) all authors reported our primary outcome of the number of patients using RRT;(4) all studies clearly compare early versus late vasopressin initiation with clinically relevant secondary outcomes.
- Condition Being Studied
- Septic shock, which is the most severe form of sepsis, is a life-threatening organ failure caused by an abnormal response of a host . Septic shock is always associated with unacceptably high mortality and even long-term morbidity for many of those who survive .The main characteristics of septic shock causing hypotension are relative and absolute hypovolemia and decreased vascular tone .
- Participant
- The inclusion criteria were as follows: (1) adult patients (> 16 years) with septic shock, septic shock was classified according to the current Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis3.0); (2) RCTs as well as prospective and retrospective cohort studies;(3) all authors reported our primary outcome of the number of patients using RRT;(4) all studies clearly compare early versus late vasopressin initiation with clinically relevant secondary outcomes. The exclusion criteria were as follows:review or conference abstract articles and studies about pediatric or animal.
- Animal
- Human Disease Modelled
- Intervention
- patients receiving vasopressin infusion within 7 h after diagnosis of septic shock
- Comparator Control
- patients receiving no vasopressin infusion or vasopressin infusion beyond 7 h after diagnosis of septic shock
- Main Outcome
- The number of patients using RRT
- Outcome Measure
- Additional Outcome
- mortality in hospital, ICU length of stay and hospital length of stay
- Study Method
- Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Cang Zhang [email protected]
- Organisational Affiliation
- The First Affiliated Hospital of Guangzhou Medical University
- Funding Source
- The First Affiliated Hospital of Guangzhou Medical University
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-12-05
- Registration Date
- 2023-12-15
- Anticipated Start Date
- 2023-09-01
- Anticipated Completion Date
- 2024-01-31
- Title Cn
- 早期使用加压素是否更可能减少脓毒性休克中肾脏替代治疗的使用？一项系统评价与Meta分析
- Title En
- Will early use of vasopressin be more likely to reduce the use of RRT in septic shock? A systematic review and meta-analysis
- Bilingual Status
- complete