Meta AnalysisID 7938
维生素K补充治疗重症COVID-19患者：一项系统评价与Meta分析方案
CRD42023405811
What is the efficacy of vitamin K supplementation for the treatment of severe COVID-19 patients？
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7938
- Evidence Id
- 16496
- Core Evidence Id
- 16496
- Source Meta Analysis Id
- 7940
- Herb2 Meta Analysis Id
- HBMA007940
- Crd Id
- CRD42023405811
- Title
- Vitamin K supplementation for the treatment of severe COVID-19 patients: a protocol for systematic review and meta-analysis
- Review Question
- What is the efficacy of vitamin K supplementation for the treatment of severe COVID-19 patients？
- Study Type Included
- Randomized controlled trials (RCTs) that explore the efficacy of Vitamin K supplementation in the treatment of severe COVID-19 patients.
- Condition Being Studied
- Severe COVID-19. Vitamin K treatment.
- Participant
- Inclusion criteria: (1) Patients were diagnosed with severe COVID-19; (2) Patient age ≥ 18 years; (3) Patients with a mini-mental state examination score ≥ 21. Exclusion criteria: (1) Patients with abnormal coagulation function; (2) Patients take vitamin K preparations or vitamin K antagonists for a long time; (3) Patients with severe liver failure.
- Animal
- Human Disease Modelled
- Intervention
- Treatment group: Vitamin K1 injection is injected intramuscularly, 10mg each time, 1-2 times a day.
- Comparator Control
- Control group: Blank control, follow routine treatment guidelines.
- Main Outcome
- (1) Routine blood test (Including RBC, Hb, WBC, PLT, etc); (2) C-reactive protein; (3) Interleukin-6 (IL-6); (4) Mechanical ventilation time; (5) ICU stay; (6) Quality of Life (QOL).
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- COVID-19; Dietary Supplements; Humans; Meta-Analysis as Topic; Systematic Reviews as Topic; Vitamins
- Contact
- Li Liu [email protected]
- Organisational Affiliation
- Zhuzhou Central Hospital http://www.zzszxyy.cn/
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-03-08
- Registration Date
- 2023-03-08
- Anticipated Start Date
- 2023-02-28
- Anticipated Completion Date
- 2023-12-31
- Title Cn
- 维生素K补充治疗重症COVID-19患者：一项系统评价与Meta分析方案
- Title En
- Vitamin K supplementation for the treatment of severe COVID-19 patients: a protocol for systematic review and meta-analysis
- Bilingual Status
- complete