Meta AnalysisID 7899

硒与动脉粥样硬化:Meta分析

CRD42023475750

The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of Selenium for Atherosclerosis patients.

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Record Fields

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Meta Analysis Id
7899
Evidence Id
16457
Core Evidence Id
16457
Source Meta Analysis Id
7895
Herb2 Meta Analysis Id
HBMA007895
Crd Id
CRD42023475750
Title
Selenium and Atherosclerosis: a meta-analysis
Review Question
The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of Selenium for Atherosclerosis patients.
Study Type Included
Randomized controlled trial
Condition Being Studied
Atherosclerosis is a leading cause of vascular disease worldwide. Its major clinical manifestations include ischemic heart disease, ischemic stroke, and peripheral arterial disease. Despite advances in controlling risk factors in many high-income countries, atherosclerotic cardiovascular disease now predominates in lower-income areas. The Global Burden of Disease study shows that world prevalence of ischemic heart disease has increased from about 100 million in 1990 to over 180 million cases in 2019 . With global trends towards a decrease in LDL and the introduction of highly effective therapies for lowering LDL, as well as inexpensive and efficacious antihypertensive therapies, these drivers of chronic risk contribute less today than in previous years. However, the current treatment of atherosclerosis is varied, and there is still little research on selenium and aortic atherosclerosis.Thus, we initiated this study.
Participant
Adults with atherosclerotic, Serum selenium content, Relationship between serum selenium and aortic atherosclerosis
Animal
Human Disease Modelled
Intervention
Prevalence and severity of aortic atherosclerosis in selenium-rich population
Comparator Control
Prevalence and severity of aortic atherosclerosis in people with normal selenium levels
Main Outcome
relative risk(RR)
Outcome Measure
Additional Outcome
Study Method
Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
Lili Yang, Jiasen Sun [email protected]
Organisational Affiliation
Ankang Central Hospital;Institute of Medicine Nursing, Hubei University of Medicine;Laboratory of Integrative Chinese and Western Medicine, the First Affiliated Hospital of Dalian Medical University
Funding Source
No
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-10-24
Registration Date
2023-11-08
Anticipated Start Date
2023-10-23
Anticipated Completion Date
2024-04-23
Title Cn
硒与动脉粥样硬化:Meta分析
Title En
Selenium and Atherosclerosis: a meta-analysis
Bilingual Status
complete