Meta AnalysisID 7896

硒改善脑卒中患者结局的疗效:随机临床试验的系统评价

CRD42023452445

Is Selenium Supplementation Beneficial in Acute Ischemic Stroke?

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Record Fields

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Meta Analysis Id
7896
Evidence Id
16454
Core Evidence Id
16454
Source Meta Analysis Id
7893
Herb2 Meta Analysis Id
HBMA007893
Crd Id
CRD42023452445
Title
Efficacy of selenium in improving the outcomes of stroke patients: A systematic review of Randomized Clinical Trials.
Review Question
Is Selenium Supplementation Beneficial in Acute Ischemic Stroke?
Study Type Included
Both experimental (clinical trials: randomized and nonrandomized) and observational (cohort, case series, case-control, cross-sectional) studies.
Condition Being Studied
Stroke is a leading cause of mortality, accounting for 11.8% of all deaths globally. It represents the second most common cause of death worldwide and a significant cause of long-term morbidity. Although the brain is incapable of regeneration, the element Selenium (Se) has been found to have a role in regenerating the antioxidant systems and improving cell proliferation and viability. So, Selenium can provide a promising solution for patients with ischemic and hemorrhagic stroke.
Participant
Patients with Stroke
Animal
Human Disease Modelled
Intervention
Selenium
Comparator Control
Placbeo
Main Outcome
Mortality and National institute of health stroke scale (NIHSS)
Outcome Measure
Additional Outcome
Modified ranking scale (MRS)
Study Method
Intervention, Systematic review
Keyword
Dietary Supplements; Humans; Ischemia; Randomized Controlled Trials as Topic; Selenium; Stroke
Contact
Rahma Sameh Shaheen [email protected]
Organisational Affiliation
benha university
Funding Source
There is no funding received for this research.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Egypt
Review Stage
Review Ongoing
First Submission Date
2023-08-07
Registration Date
2023-08-18
Anticipated Start Date
2023-05-15
Anticipated Completion Date
2023-09-21
Title Cn
硒改善脑卒中患者结局的疗效:随机临床试验的系统评价
Title En
Efficacy of selenium in improving the outcomes of stroke patients: A systematic review of Randomized Clinical Trials.
Bilingual Status
complete