Meta AnalysisID 7895

补硒对代谢性疾病患者心血管危险因素的影响:随机对照试验的系统评价与Meta分析

CRD42023439196

placebo, blank control;The purpose of this systematic review and meta-analysis was to evaluate the effect of selenium supplementation on cardiovascular risk factors with metabolic diseases. p:metabolic diseases I:seleniu

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Record Fields

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Meta Analysis Id
7895
Evidence Id
16453
Core Evidence Id
16453
Source Meta Analysis Id
7892
Herb2 Meta Analysis Id
HBMA007892
Crd Id
CRD42023439196
Title
The Effects of Selenium Supplementation on Cardiovascular Risk Factors Among Patients with Metabolic Diseases:A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Review Question
placebo, blank control;The purpose of this systematic review and meta-analysis was to evaluate the effect of selenium supplementation on cardiovascular risk factors with metabolic diseases. p:metabolic diseases I:selenium supplementation C:placebo, blank control O:Insulin, FPG, QUICKI, HOMA-B, HOMA-IR, blood lipid, hs-CRP, TAC, NO, GSH, Weight, and BMI.
Study Type Included
RCTs
Condition Being Studied
Metabolic syndrome is a group of clinical syndromes that are characterized by a combination of obesity, hyperglycemia, hypertension, and dyslipidemia. Patients with metabolic syndrome usually have cardiovascular risk factors, including disorders of glucolipid metabolism, inflammatory oxidative stress, and body weight and BMI, and are at high risk for developing cardiovascular disease. Selenium supplementation has been reported to improve cardiovascular risk factors in patients with metabolic diseases.
Participant
Metabolic disease-related patients
Animal
Human Disease Modelled
Intervention
The experimental group received selenium supplementation treatment.
Comparator Control
The control group received placebo treatment.
Main Outcome
Insulin, FPG, QUICKI, HOMA-B, HOMA-IR Measures of effect The indicators with the same unit was selected mean difference(MD); The standardized mean difference(SMD) was used for the indicators with inconsistent units.
Outcome Measure
Additional Outcome
blood lipid, hs-CRP, TAC, NO, GSH, Weight, BMI Measures of effect The indicators with the same unit was selected mean difference(MD); The standardized mean difference(SMD) was used for the indicators with inconsistent units.
Study Method
Meta-analysis, Systematic review
Keyword
Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Dietary Supplements; Humans; Insulin; Insulin, Regular, Human; Lipids; Metabolic Diseases; Randomized Controlled Trials as Topic; Risk Factors; Selenium
Contact
weixiu qiu [email protected]
Organisational Affiliation
Weifang Medical University
Funding Source
Weifang Medical University
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-07-10
Registration Date
2023-07-21
Anticipated Start Date
2023-05-21
Anticipated Completion Date
2023-08-10
Title Cn
补硒对代谢性疾病患者心血管危险因素的影响:随机对照试验的系统评价与Meta分析
Title En
The Effects of Selenium Supplementation on Cardiovascular Risk Factors Among Patients with Metabolic Diseases:A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Bilingual Status
complete