Meta AnalysisID 7878
产前邻苯二甲酸酯暴露与儿童过敏性疾病风险的关联：一项队列研究的系统评价和Meta分析
CRD42023443700
Phthalates, a class of the most common environmental contaminates and endocrine disruptors, can be easily released into the surrounding environment and phthalates get into human body through inhalation, digestion and der
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7878
- Evidence Id
- 16436
- Core Evidence Id
- 16436
- Source Meta Analysis Id
- 7874
- Herb2 Meta Analysis Id
- HBMA007874
- Crd Id
- CRD42023443700
- Title
- Association of Prenatal Exposure to Phthalates with risks of childhood allergic diseases: A systematic review and meta-analysis of cohort studies
- Review Question
- Phthalates, a class of the most common environmental contaminates and endocrine disruptors, can be easily released into the surrounding environment and phthalates get into human body through inhalation, digestion and dermal absorption.It has been reported that prenatal exposure to phthalates can increase the risk of childhood allergic diseases, and presenting sex differences and phthalate classes-specificity. and we hope to review the existing literature to explore their association with childhood allergic diseases. The principles of PECOS apply in this article.
- Study Type Included
- The type of study design is cohort study.
- Condition Being Studied
- Allergic diseases, the most common chronic health problems in children, bothers more than 20% of the population worldwide.Phthalates, a class of the most common environmental contaminates and endocrine disruptors, are globally used as plasticizers to impart flexibility and durability in industrial and commercial products, especially in polyvinyl chloride (PVC) plastics.By reviewing the existing literature, we hope to explore the relationship between prenatal exposure to phthalates and allergic diseases in children, and provide some scientific insights for the prevention of allergic diseases in children.
- Participant
- Case group：1. Self-reported allergic diseases diagnosed by a physician for children; 2.Use anti-allergy medications for children; Control group : healthy individuals without allergic diseases for children.
- Animal
- Human Disease Modelled
- Intervention
- Exposure to at least one of the phthalates during pregnancy
- Comparator Control
- Comparison of results between those exposed to higher levels of phthalates and those exposed to lower levels in pregnant women (or below detection levels) (usually the highest concentration compared to the lowest concentration, or the highest quartile estimate of exposure compared to the lowest quartile estimate)
- Main Outcome
- allergic diseases Measures of effect odds ratios
- Outcome Measure
- Additional Outcome
- None or Not applicable
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Digestion; Endocrine Disruptors; Female; Human Body; Humans; Hypersensitivity; Male; Pregnancy; Prenatal Exposure Delayed Effects; phthalic acid
- Contact
- Jingxuan Yang [email protected]
- Organisational Affiliation
- Sichuan University
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-07-09
- Registration Date
- 2023-07-20
- Anticipated Start Date
- 2023-07-09
- Anticipated Completion Date
- 2023-08-09
- Title Cn
- 产前邻苯二甲酸酯暴露与儿童过敏性疾病风险的关联：一项队列研究的系统评价和Meta分析
- Title En
- Association of Prenatal Exposure to Phthalates with risks of childhood allergic diseases: A systematic review and meta-analysis of cohort studies
- Bilingual Status
- complete