Meta AnalysisID 7875
产前邻苯二甲酸酯暴露与出生体重关联的系统评价和Meta分析
CRD42023402227
(P) infants without restriction on regions and race, (E) prenatal phthalate exposure, (C) participants from the same study, (O) birth weight, and (S) cohort or cross-sectional studies exploring associations between phtha
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7875
- Evidence Id
- 16433
- Core Evidence Id
- 16433
- Source Meta Analysis Id
- 7871
- Herb2 Meta Analysis Id
- HBMA007871
- Crd Id
- CRD42023402227
- Title
- Systematic review and meta-analysis of associations between prenatal exposure to phthalates and birth weight.
- Review Question
- (P) infants without restriction on regions and race, (E) prenatal phthalate exposure, (C) participants from the same study, (O) birth weight, and (S) cohort or cross-sectional studies exploring associations between phthalate exposure and birth weight and reporting estimated effects.
- Study Type Included
- Cohort or cross-sectional studies exploring the relationship between phthalate exposure and birth weight will all likely be included in this study.
- Condition Being Studied
- Low birth weight (LBW) is generally recognized as a risk factor for poor health. Infants with LBW are at an increased risk of infection and poor neurodevelopmental and developmental problems during infancy and childhood. Animal studies have demonstrated that decreased birth weight is one of the most sensitive outcomes of prenatal phthalate exposure. Several studies found positive associations between prenatal phthalate exposure and birth weight, others have shown null or inverse associations. The potential adverse effects of phthalate toxicity on fetal health outcomes are attracting growing concern.
- Participant
- Women with internal exposure levels of phthalates from pregnancy and with information on birth weight of offspring will be included.
- Animal
- Human Disease Modelled
- Intervention
- A history of prenatal phthalate exposure in the offspring is considered when phthalates are detected in biological samples from pregnant women.
- Comparator Control
- If phthalates are not detected in biological samples from pregnant women, it is assumed that the offspring do not have a history of prenatal phthalate exposure. Then the individual will be excluded from the study.
- Main Outcome
- Prenatal exposure to phthalates may negatively affect birth weight.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Birth Weight; Cross-Sectional Studies; Female; Humans; Infant; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; phthalic acid
- Contact
- Shihao Jin [email protected]
- Organisational Affiliation
- Tianjin Medical University
- Funding Source
- National Natural Science Foundation of China
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-02-23
- Registration Date
- 2023-03-05
- Anticipated Start Date
- 2022-08-07
- Anticipated Completion Date
- 2023-04-07
- Title Cn
- 产前邻苯二甲酸酯暴露与出生体重关联的系统评价和Meta分析
- Title En
- Systematic review and meta-analysis of associations between prenatal exposure to phthalates and birth weight.
- Bilingual Status
- complete