Meta AnalysisID 7870
膳食磷对健康成人餐后代谢反应的影响
CRD42023489337
What is the effect of dietary phosphorus supplementation [I] on postprandial metabolism [O], as compared to the effect of low or depleted phosphorus intake levels [C], in healthy adults [P]?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7870
- Evidence Id
- 16428
- Core Evidence Id
- 16428
- Source Meta Analysis Id
- 7867
- Herb2 Meta Analysis Id
- HBMA007867
- Crd Id
- CRD42023489337
- Title
- The Impact of Dietary Phosphorus on Postprandial Metabolic Responses in Healthy Adults
- Review Question
- What is the effect of dietary phosphorus supplementation [I] on postprandial metabolism [O], as compared to the effect of low or depleted phosphorus intake levels [C], in healthy adults [P]?
- Study Type Included
- Only intervention studies with an evaluation of metabolic outcomes are eligible to be included in this review. Observational studies will be excluded. Experimental studies will be included if they are randomized controlled trials; parallel or crossover studies.
- Condition Being Studied
- Dietary phosphorus partakes a crucial role in energy metabolism, by being responsible for the phosphorylation of glucose; an essential step in insulin signaling and intracellular glucose uptake, in addition to its role in ATP production. Any compromise in postprandial phosphate levels may induce metabolic changes that may favor the development of different components of the metabolic syndrome, such as glucose intolerance and obesity.
- Participant
- Participants shall be healthy adults (18 to 64 years), and not belonging to any group with any diagnosed diseases.
- Animal
- Human Disease Modelled
- Intervention
- Phosphorus supplementation (in any form)
- Comparator Control
- Non-exposed control group, placebo, or phosphate binders/chelators.
- Main Outcome
- Primary outcomes: postprandial metabolism, including thermogenesis (measured by substrate oxidation), postprandial glycemia (measured by postprandial glucose and insulin levels), and postprandial lipidemia (measured by postprandial lipid panels). Measures of effect Above or below normal plasma levels of lipid panels and glycemic parameters, and percentage of substrate oxidation
- Outcome Measure
- Additional Outcome
- Body composition, energy intake, and satiety Measures of effect appetite scores and BMI measurements
- Study Method
- Intervention, Narrative synthesis, Prevention, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Rania El Khoury [email protected]
- Organisational Affiliation
- University of Nottingham www.nottingham.ac.uk
- Funding Source
- This systematic review will be undertaken in collaboration with the University of Nottingham in England and the American University of Beirut in Lebanon.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Lebanon
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-12-03
- Registration Date
- 2023-12-14
- Anticipated Start Date
- 2023-12-04
- Anticipated Completion Date
- 2024-03-01
- Title Cn
- 膳食磷对健康成人餐后代谢反应的影响
- Title En
- The Impact of Dietary Phosphorus on Postprandial Metabolic Responses in Healthy Adults
- Bilingual Status
- complete