Meta AnalysisID 7859

常用缩宫素给药途径预防产后出血的不良副作用

CRD42023407571

To compare the adverse side effects of the common routes of oxytocin for preventing postpartum hemorrhage.

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Record Fields

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Meta Analysis Id
7859
Evidence Id
16417
Core Evidence Id
16417
Source Meta Analysis Id
7857
Herb2 Meta Analysis Id
HBMA007857
Crd Id
CRD42023407571
Title
Adverse side effects of common routes of oxytocin for preventing postpartum hemorrhage
Review Question
To compare the adverse side effects of the common routes of oxytocin for preventing postpartum hemorrhage.
Study Type Included
Inclusion: all published randomized controlled trials (RCTs), irrespective of blinding status. Exclusion: quasi-randomized, cross-over, or observational trials will not be included, as these types of studies are more subject to bias.
Condition Being Studied
Postpartum hemorrhage (PPH) is still the most common form of major obstetric hemorrhage. It remains a leading cause of maternal morbidity and mortality worldwide, even in high-income countries. Oxytocin is the first-choice used uterotonic agent as a result of its high efficacy and low incidence of adverse effects to prevent postpartum hemorrhage. It is commonly administered intramuscularly injection, intravenously infusion, or intravenously bolus. The aim of this study is to compare the adverse side effects of the common routes of oxytocin for preventing postpartum hemorrhage.
Participant
Women who undergo cesarean section or vaginal deliveries.
Animal
Human Disease Modelled
Intervention
Intramuscularly injection oxytocin for preventing postpartum hemorrhage.
Comparator Control
Other routes oxytocin for preventing postpartum hemorrhage.
Main Outcome
Vomiting, according to the definitions of the respective study authors.
Outcome Measure
Additional Outcome
Nausea, according to the definitions of the respective study authors. Headache, according to the definitions of the respective study authors.
Study Method
Meta-analysis, Systematic review
Keyword
Drug-Related Side Effects and Adverse Reactions; Female; Humans; Iatrogenic Disease; Oxytocics; Oxytocin; Postpartum Hemorrhage; Postpartum Period; Pregnancy
Contact
Dazhi Fan [email protected]
Organisational Affiliation
Southern Medical University Affiliated Maternal and Child Health Hospital of Foshan
Funding Source
Southern Medical University Affiliated Maternal & Child Health Hospital of Foshan
Other Selection Criteria
Final Publication
https://PubMed.ncbi.nlm.nih.gov/38186656/
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Completed published
First Submission Date
2023-03-13
Registration Date
2023-03-24
Anticipated Start Date
2023-03-15
Anticipated Completion Date
2023-11-22
Title Cn
常用缩宫素给药途径预防产后出血的不良副作用
Title En
Adverse side effects of common routes of oxytocin for preventing postpartum hemorrhage
Bilingual Status
complete