Meta AnalysisID 7856
剖宫产椎管内麻醉下预防性使用去氧肾上腺素与去甲肾上腺素对母儿结局的比较：系统评价与Meta分析
CRD42023429328
Does norepinephrine as compared to phenylephrine improve fetomaternal outcomes in terms of fatal acidosis, APGAR score and maternal haemodynamics?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7856
- Evidence Id
- 16414
- Core Evidence Id
- 16414
- Source Meta Analysis Id
- 7853
- Herb2 Meta Analysis Id
- HBMA007853
- Crd Id
- CRD42023429328
- Title
- Comparison of prophylactic phenylephrine and norepinephrine on feto-maternal outcomes following cesarean delivery under neuraxial anaesthesia: A systematic review and meta-analysis
- Review Question
- Does norepinephrine as compared to phenylephrine improve fetomaternal outcomes in terms of fatal acidosis, APGAR score and maternal haemodynamics?
- Study Type Included
- Randomised controlled trials
- Condition Being Studied
- Pregnant women undergoing Caesarean section under neuraxial anaesthesia
- Participant
- Inclusion criteria - Term, singleton/twin pregnancy undergoing elective/emergency Caesarean section under neuraxial anaesthesia Exclusion criteria - peripartum bleeding, preexisting or pregnancy-related hypertension, preeclampsia, use of antihypertensive medication during pregnancy, known cardiovascular or cerebrovascular disease, body mass index (BMI) > 40 kg/m2, body weight less than 50 kg or more than 100 kg, height less than 150 cm or greater than 180 cm, age <18 years, any contraindication to regional anesthesia such as thrombocytopenia or coagulation abnormality
- Animal
- Human Disease Modelled
- Intervention
- Prophylactic norepinephrine infusion or bolus
- Comparator Control
- Prophylactic phenylephrine infusion or bolus
- Main Outcome
- Umbilical artery pH Measures of effect Median with interquartile range/Mean with standard deviation
- Outcome Measure
- Additional Outcome
- APGAR score, Incidence of Maternal bradycardia, hypotension, hypertension, nausea and vomiting
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Acidosis; Apgar Score; Female; Hemodynamics; Humans; Infant, Newborn; Norepinephrine; Phenylephrine; Pregnancy
- Contact
- Anjishnujit Bandyopadhyay [email protected]
- Organisational Affiliation
- All India Institute of Medical Sciences
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-05-27
- Registration Date
- 2023-06-08
- Anticipated Start Date
- 2023-06-07
- Anticipated Completion Date
- 2023-07-07
- Title Cn
- 剖宫产椎管内麻醉下预防性使用去氧肾上腺素与去甲肾上腺素对母儿结局的比较：系统评价与Meta分析
- Title En
- Comparison of prophylactic phenylephrine and norepinephrine on feto-maternal outcomes following cesarean delivery under neuraxial anaesthesia: A systematic review and meta-analysis
- Bilingual Status
- complete