Meta AnalysisID 7850
肌醇对辅助生殖技术女性卵母细胞和胚胎质量的有效性：系统评价与Meta分析
CRD42023433328
Can inositol treatment be effective in women undergoing assisted reproductive technologies (ovulation induction cycles/IVF /intrauterine insemination/ICSI) for oocyte and embryo quality?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7850
- Evidence Id
- 16408
- Core Evidence Id
- 16408
- Source Meta Analysis Id
- 7847
- Herb2 Meta Analysis Id
- HBMA007847
- Crd Id
- CRD42023433328
- Title
- Effectiveness of inositol on oocyte and embryo quality in women undergoing reproductive technologies: systematic review and meta-analysis.
- Review Question
- Can inositol treatment be effective in women undergoing assisted reproductive technologies (ovulation induction cycles/IVF /intrauterine insemination/ICSI) for oocyte and embryo quality?
- Study Type Included
- Randomized clinical trials only in English will be included.
- Condition Being Studied
- Inositol is a C6 sugar alcohol belonging to the B-group vitamins. It plays a key role in all aspects of cell physiology including lipid synthesis, cell morphogenesis and cell membrane functions. The use of inositol and its isoforms (particularly Myo-inositol) as a supplement to ART programs is being actively researched and discussed by the scientific community. Studies have demonstrated that this molecule reduces insulin resistance and improves ovarian function, oocyte quality and pregnancy rates Therefore, we decided evaluate the impact of inositol on oocyte and embryo quality in women undergoing ART.
- Participant
- • Female patients 18-45 ages. • Patients undergoing assisted reproductive technologies (ovulation induction cycles/IVF /intrauterine insemination/ICSI)
- Animal
- Human Disease Modelled
- Intervention
- • inositol
- Comparator Control
- • No treatment or placebo
- Main Outcome
- • Oocyte quality • Oocyte maturation • Embryo quality • The number of retrieved oocytes and follicle count Measures of effect Mean +- SD
- Outcome Measure
- Additional Outcome
- • Impantation rate • Clinical pregnancy rate • Live birth rate Measures of effect Risk ratio
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Female; Fertilization in Vitro; Humans; Inositol; Insemination; Oocytes; Ovulation Induction; Sperm Injections, Intracytoplasmic
- Contact
- Ekaterina Krylova [email protected]
- Organisational Affiliation
- Sechenov University
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Russian Federation
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-07
- Registration Date
- 2023-06-18
- Anticipated Start Date
- 2023-06-07
- Anticipated Completion Date
- 2023-12-07
- Title Cn
- 肌醇对辅助生殖技术女性卵母细胞和胚胎质量的有效性：系统评价与Meta分析
- Title En
- Effectiveness of inositol on oocyte and embryo quality in women undergoing reproductive technologies: systematic review and meta-analysis.
- Bilingual Status
- complete