Meta AnalysisID 7788

硫酸镁治疗慢性阻塞性肺疾病急性加重有效性和安全性的Meta分析

CRD42023484670

The efficacy and safety of intravenous magnesium sulfate in patients with acute exacerbation of chronic obstructive pulmonary disease.

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Record Fields

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Meta Analysis Id
7788
Evidence Id
16346
Core Evidence Id
16346
Source Meta Analysis Id
7786
Herb2 Meta Analysis Id
HBMA007786
Crd Id
CRD42023484670
Title
A meta-analysis of the effectiveness and safety of magnesium sulfate in the treatment of AECOPD
Review Question
The efficacy and safety of intravenous magnesium sulfate in patients with acute exacerbation of chronic obstructive pulmonary disease.
Study Type Included
Articles analyzing the effectiveness of magnesium sulfate in treating acute exacerbations of COPD were included. Study patients were diagnosed according to guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease. The outcomes included clinical efficacy, lung function, arterial blood gases, and adverse effects. The exclusion criteria were as following: (1) non-human studies; (2) non-comparative studies; (3) Studies of multiple interventions; (4) non-original studies (letters, reviews, editorials).
Condition Being Studied
Chronic obstructive pulmonary disease (COPD) is a chronic and progressive disease, often punctuated by recurrent flare-ups or exacerbations. Magnesium sulfate, having a bronchodilatory effect, may have a potential role as an adjunct treatment in COPD exacerbations. However, comprehensive evidence of its effects is required to facilitate clinical decision-making.
Participant
Articles analyzing the effectiveness of magnesium sulfate in treating acute exacerbations of COPD were included. Study patients were diagnosed according to guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease. The outcomes included clinical efficacy, lung function, arterial blood gases, and adverse effects. The exclusion criteria were as following: (1) non-human studies; (2) non-comparative studies; (3) Studies of multiple interventions; (4) non-original studies (letters, reviews, editorials).
Animal
Human Disease Modelled
Intervention
Intravenous magnesium sulfate
Comparator Control
placebo
Main Outcome
Clinical efficacy, lung function, PEFR
Outcome Measure
Additional Outcome
Arterial blood gas, DSS, RR, adverse reactions
Study Method
Meta-analysis, Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
Hui Li [email protected]
Organisational Affiliation
Department of General Medicine, The First Affiliated Hospital of Xinjiang Medical University
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-11-19
Registration Date
2023-11-30
Anticipated Start Date
2023-05-01
Anticipated Completion Date
2023-12-26
Title Cn
硫酸镁治疗慢性阻塞性肺疾病急性加重有效性和安全性的Meta分析
Title En
A meta-analysis of the effectiveness and safety of magnesium sulfate in the treatment of AECOPD
Bilingual Status
complete