Meta AnalysisID 7786
硫酸镁与硝苯地平抑制早产的随机对照试验或队列研究的系统评价与Meta分析
CRD42023481966
The population was pregnant women with PTB, the intervention being examined was magnesium sulfate, the comparator was nifedipine, and the outcomes focused on efficacy and safety profiles.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7786
- Evidence Id
- 16344
- Core Evidence Id
- 16344
- Source Meta Analysis Id
- 7784
- Herb2 Meta Analysis Id
- HBMA007784
- Crd Id
- CRD42023481966
- Title
- Systematic review and meta-analysis of randomized controlled trials or cohort studies of magnesium sulfate versus nifedipine for inhibition of preterm labor.
- Review Question
- The population was pregnant women with PTB, the intervention being examined was magnesium sulfate, the comparator was nifedipine, and the outcomes focused on efficacy and safety profiles.
- Study Type Included
- The included literature in this study comprised of randomized controlled trials (RCTs) or cohort studies.
- Condition Being Studied
- Preterm birth (PTB) is defined as birth prior to 37 weeks of gestation. The estimated global preterm birth rate for 2020 was 9.9%. Complications associated with PTB are the most common cause of neonatal deaths and the leading cause of death among children under 5 years old.
- Participant
- The population was women with PTB. Observational studies, conference articles, letters, reviews, and studies with insufficiently reliable data were excluded from analysis.
- Animal
- Human Disease Modelled
- Intervention
- The intervention was magnesium sulfate for preterm birth.
- Comparator Control
- The comparator was nifedipine preterm birth.
- Main Outcome
- The outcomes were treatment efficacy, including time to drug onset, whether prolongation of gestational age was more than 48h or 7 days; Measures of effect We used summary relative risk (RR) for dichotomous data and mean difference (MD) for continuous data, along with their corresponding 95% confidence intervals (CIs).
- Outcome Measure
- Additional Outcome
- The outcomes were maternal adverse effects, including tachycardia, hypotension; and neonatal safety profiles, such as birthweight; Apgar score. Measures of effect We used summary relative risk (RR) for dichotomous data and mean difference (MD) for continuous data, along with their corresponding 95% confidence intervals (CIs).
- Study Method
- Diagnostic, Individual patient data (IPD) meta-analysis, Intervention, Meta-analysis, Prevention, Synthesis of qualitative studies, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- fan jianing [email protected]
- Organisational Affiliation
- Nanjing Women and Children's Healthcare Hospital https://www.njfybjy.com/
- Funding Source
- Nanjing Women and Children's Healthcare Hospital
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-11-11
- Registration Date
- 2023-11-22
- Anticipated Start Date
- 2023-05-01
- Anticipated Completion Date
- 2023-12-11
- Title Cn
- 硫酸镁与硝苯地平抑制早产的随机对照试验或队列研究的系统评价与Meta分析
- Title En
- Systematic review and meta-analysis of randomized controlled trials or cohort studies of magnesium sulfate versus nifedipine for inhibition of preterm labor.
- Bilingual Status
- complete