Meta AnalysisID 7784

硫酸镁与神经肌肉阻滞剂用于气管插管的有效性和安全性比较。

CRD42023473617

PICOS: P (Population): Adults, over 18 years. I (Intervention): Magnesium sulfate. C (Comparators): Neuromuscular blockers. O (Outcome): effectiveness and safety. S (Study type): randomized controlled trials (RCTs). What

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Record Fields

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Meta Analysis Id
7784
Evidence Id
16342
Core Evidence Id
16342
Source Meta Analysis Id
7782
Herb2 Meta Analysis Id
HBMA007782
Crd Id
CRD42023473617
Title
Effectiveness and safety of magnesium sulfate compared to neuromuscular blockers for tracheal intubation.
Review Question
PICOS: P (Population): Adults, over 18 years. I (Intervention): Magnesium sulfate. C (Comparators): Neuromuscular blockers. O (Outcome): effectiveness and safety. S (Study type): randomized controlled trials (RCTs). What is the effectiveness and safety of magnesium sulfate compared to neuromuscular blockers for tracheal intubation in general anesthesia?
Study Type Included
Randomized controlled trials (RCTs).
Condition Being Studied
Magnesium sulfate has the characteristics of providing analgesia, control of autonomic reflexes and muscle relaxation, being used in clinical practice. In the clinical context, the use of this agent to ensure adequate conditions for tracheal intubation remains controversial. In this sense, the objective of this work is to determine the effectiveness and safety of magnesium sulfate in the management of tracheal intubation in adults submitted to general anesthesia.
Participant
Adult patients under general anesthesia.
Animal
Human Disease Modelled
Intervention
Administration of magnesium sulfate to perform tracheal intubation.
Comparator Control
Compared to the use of neuromuscular blockers in tracheal intubation.
Main Outcome
Clinical condition of tracheal intubation, time to tracheal intubation, hemodynamic responses, adverse effects, complications, participants characteristics (ASA classification), clinical scenario (emergency, surgery, ICU), Mallampati index, magnesium sulfate dosage.
Outcome Measure
Additional Outcome
The incidence of adverse effects such as hemodynamic responses.
Study Method
Intervention, Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
Laura Albuquerque [email protected]
Organisational Affiliation
Universidade Federal de Alagoas https://ufal.br/
Funding Source
None.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English, Portuguese-Brazil
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2023-10-17
Registration Date
2023-10-28
Anticipated Start Date
2023-08-07
Anticipated Completion Date
2024-08-07
Title Cn
硫酸镁与神经肌肉阻滞剂用于气管插管的有效性和安全性比较。
Title En
Effectiveness and safety of magnesium sulfate compared to neuromuscular blockers for tracheal intubation.
Bilingual Status
complete