Meta AnalysisID 7755
叶黄素的神经药理学和临床效应：一项系统评价
CRD42023439052
What is the relationship between lutein levels and neurodegenerative diseases in human?
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Record Fields
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- Meta Analysis Id
- 7755
- Evidence Id
- 16313
- Core Evidence Id
- 16313
- Source Meta Analysis Id
- 7753
- Herb2 Meta Analysis Id
- HBMA007753
- Crd Id
- CRD42023439052
- Title
- The Neuropharmacological and clinical effects of Lutein: A systematic review
- Review Question
- What is the relationship between lutein levels and neurodegenerative diseases in human?
- Study Type Included
- All Randomized controlled trials , case-control, cohort, cross-sectional, and interventional studies were be included.
- Condition Being Studied
- The systematic review focuses on neurodegenerative diseases, which are a group of disorders characterized by the progressive degeneration of the structure and function of the nervous system. Neurodegenerative diseases include conditions such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and others.
- Participant
- Inclusion criteria: Studies that investigated the relationship between lutein and neurodegenerative diseases were included. In vitro and in vivo studies and case reports were excluded.
- Animal
- Human Disease Modelled
- Intervention
- The interventions or exposures to be reviewed include: lutein supplementation, Dietary intake of lutein, Plasma concentrations of lutein. However, simultaneous intake of two or more types of carotenoids is allowed if the combined carotenoids are of similar function and bio-distribution (for example, lutein and zeaxanthin).
- Comparator Control
- Non-exposed control group: In several studies, the intervention or exposure (such as lutein supplementation or dietary intake of carotenoids) is compared to a non-exposed control group.Placebo group: In some clinical trials, the intervention group receiving lutein supplementation is compared to a placebo group.
- Main Outcome
- The effects of lutein on cognitive performance , oxidative stress markers , disease progression or mortality and lipid profile.The studies included in this review evaluated cognitive function, as well as different biomarkers or tests.
- Outcome Measure
- Additional Outcome
- cognitive performance , oxidative stress markers , disease progression or mortality and lipid profile .
- Study Method
- Systematic review
- Keyword
- Humans; Lutein; Neurodegenerative Diseases; Neuropharmacology
- Contact
- atefeh arab firozjae [email protected]
- Organisational Affiliation
- mazandaran university of medical science
- Funding Source
- this research is supported by The Medicinal Plants Research Center, Mazandaran University of Medical Science, Sari, Iran.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-07-19
- Registration Date
- 2023-07-31
- Anticipated Start Date
- 2023-07-01
- Anticipated Completion Date
- 2023-08-19
- Title Cn
- 叶黄素的神经药理学和临床效应：一项系统评价
- Title En
- The Neuropharmacological and clinical effects of Lutein: A systematic review
- Bilingual Status
- complete