Meta AnalysisID 7752

他汀类药物使用与新发糖尿病的性别特异性风险:随机试验的Meta分析

CRD42023413092

To estimate sex differences in statin-related risk of incident diabetes in randomized controlled trials or crossover trials of statins vs. placebo for primary or second prevention of cardiovascular disease. To estimate s

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Record Fields

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Meta Analysis Id
7752
Evidence Id
16310
Core Evidence Id
16310
Source Meta Analysis Id
7749
Herb2 Meta Analysis Id
HBMA007749
Crd Id
CRD42023413092
Title
Statin use and sex-specific risk of new-onset diabetes: a meta-analysis of randomized trials
Review Question
To estimate sex differences in statin-related risk of incident diabetes in randomized controlled trials or crossover trials of statins vs. placebo for primary or second prevention of cardiovascular disease. To estimate sex differences in statin-related risk of incident diabetes in randomized controlled trials or crossover trials of statins vs. placebo for primary prevention of cardiovascular disease. To estimate sex differences in statin-related risk of incident diabetes in randomized controlled trials or crossover trials of statins vs. placebo for secondary prevention of cardiovascular disease. To estimate sex differences in statin-related risk of incident diabetes in randomized controlled trials or crossover trials of statins vs. placebo for primary prevention of cardiovascular disease stratified by high vs. moderate CVD risk.
Study Type Included
RCT, crossover trial
Condition Being Studied
Statin-associated diabetes
Participant
Adults ≥18 years enrolled in a randomized placebo-controlled trial or crossover trial of statin vs. placebo for primary or secondary prevention of cardiovascular disease.
Animal
Human Disease Modelled
Intervention
(“statin” or “hydroxymethylglutarylcoenzyme A reductase inhibitors” or “anticholesteremic agents” or “simvastatin” or “rosuvastatin” or “pravastatin” or “atorvastatin” or “fluvastatin” or “cerivastatin” or “pitavastatin” or “lovastatin”)
Comparator Control
Placebo
Main Outcome
Incident diabetes Measures of effect relative risks, hazard ratios
Outcome Measure
Additional Outcome
Fasting blood glucose Measures of effect Not applicable
Study Method
Meta-analysis, Systematic review
Keyword
Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Randomized Controlled Trials as Topic
Contact
Pandora (Luke) Wander [email protected]
Organisational Affiliation
VA Puget Sound Health Care System/University of Washington www.uw.edu
Funding Source
No funding
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
United States of America
Review Stage
Review Ongoing
First Submission Date
2023-05-16
Registration Date
2023-05-27
Anticipated Start Date
2023-05-24
Anticipated Completion Date
2023-09-30
Title Cn
他汀类药物使用与新发糖尿病的性别特异性风险:随机试验的Meta分析
Title En
Statin use and sex-specific risk of new-onset diabetes: a meta-analysis of randomized trials
Bilingual Status
complete