Meta AnalysisID 7709

碘-125放射性粒子组织间植入治疗晚期肺癌的疗效与安全性:一项Meta分析

CRD42023469721

P: lung cancer, NSCLC I: 125I brachytherapy with chemotherapy C: chemotherapy O: complete response rate, disease control rate, 1-year survival rate, 2-year survival rate, 3-year survival rate, progress free survival (PFS

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Record Fields

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Meta Analysis Id
7709
Evidence Id
16267
Core Evidence Id
16267
Source Meta Analysis Id
7703
Herb2 Meta Analysis Id
HBMA007703
Crd Id
CRD42023469721
Title
Efficacy and safety of iodine-125 radioactive seeds brachytherapy for advanced lung cancer: a meta-analysis
Review Question
P: lung cancer, NSCLC I: 125I brachytherapy with chemotherapy C: chemotherapy O: complete response rate, disease control rate, 1-year survival rate, 2-year survival rate, 3-year survival rate, progress free survival (PFS) S: RCT
Study Type Included
RCTs
Condition Being Studied
According to the Global Cancer Statistics 2020 report, lung cancer is the second prevalent malignancy, causing 11.4% of all malignant tumors, but it remains the leading cause of cancer fatalities, accounting for approximately 1.8 million deaths (18%), with non-small cell lung cancer (NSCLC) accounting for 85% of these deaths
Participant
1 Diagnosis of NSCLC by histology or pathology. 2 The diagnosis of NSCLC was confirmed by histology or pathology. 3 TNM stage IIb-IV non-small cell lung cancer according to the 7th edition of the AJCC 2010; 4 Age greater than 18 years. 4 Age greater than 18 years.
Animal
Human Disease Modelled
Intervention
125I brachytherapy with chemotherapy
Comparator Control
chemotherapy
Main Outcome
complete response rate (CRR), disease control rate (DCR), 1-year survival rate, 2-year survival rate, 3-year survival rate
Outcome Measure
Additional Outcome
progress free survival (PFS), and treatment-related toxicity
Study Method
Meta-analysis, Systematic review
Keyword
Brachytherapy; Carcinoma, Non-Small-Cell Lung; Humans; Iodine-125; Lung Neoplasms; Randomized Controlled Trials as Topic; Survival Rate
Contact
hanming yu [email protected]
Organisational Affiliation
The fourth Affiliated Hospital of Chinese medicine University
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-10-05
Registration Date
2023-10-16
Anticipated Start Date
2023-10-07
Anticipated Completion Date
2023-11-07
Title Cn
碘-125放射性粒子组织间植入治疗晚期肺癌的疗效与安全性:一项Meta分析
Title En
Efficacy and safety of iodine-125 radioactive seeds brachytherapy for advanced lung cancer: a meta-analysis
Bilingual Status
complete