Meta AnalysisID 7702
早产儿动脉导管未闭的期待疗法：随机对照试验的Meta分析
CRD42023400977
Expectant management versus early treatment of patent ductus arteriosus in preterm infants.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7702
- Evidence Id
- 16260
- Core Evidence Id
- 16260
- Source Meta Analysis Id
- 7696
- Herb2 Meta Analysis Id
- HBMA007696
- Crd Id
- CRD42023400977
- Title
- Expectant management of patent ductus arteriosus for preterm infants: a meta-analysis of randomized controlled trials
- Review Question
- Expectant management versus early treatment of patent ductus arteriosus in preterm infants.
- Study Type Included
- RCTs
- Condition Being Studied
- PDA in preterm infants
- Participant
- Preterm infants with a PDA (irrespective of diagnostic criteria)
- Animal
- Human Disease Modelled
- Intervention
- Expectant management is defined as the absence of any pharmacological or surgical/endovascular intervention with the intention to actively close the DA other than fluid restriction, diuretics, and/or ventilator adjustments. (defined as <25% open-label pharmacological treatment with ibuprofen, indomethacin, or paracetamol and/or ligation/endovascular closure)
- Comparator Control
- Active early treatment to close the PDA
- Main Outcome
- All-cause mortality Measures of effect RR
- Outcome Measure
- Additional Outcome
- BPD (any definition) NEC (any stage) IVH (any grade) ROP (any stage) Sepsis The proportion of infants requiring surgical PDA ligation or transcatheter occlusion Duration of ventilator support (days) Duration of need for supplementary oxygen (days) Measures of effect RR and MD
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Ductus Arteriosus, Patent; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Persistent Fetal Circulation Syndrome; Randomized Controlled Trials as Topic
- Contact
- Abia Shahid [email protected]
- Organisational Affiliation
- King Edward Medical University
- Funding Source
- Not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Pakistan
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-02-21
- Registration Date
- 2023-03-04
- Anticipated Start Date
- 2023-02-18
- Anticipated Completion Date
- 2023-03-23
- Title Cn
- 早产儿动脉导管未闭的期待疗法：随机对照试验的Meta分析
- Title En
- Expectant management of patent ductus arteriosus for preterm infants: a meta-analysis of randomized controlled trials
- Bilingual Status
- complete