Meta AnalysisID 7630
药物干预对多囊卵巢综合征女性妊娠率的影响:系统评价与Meta分析
CRD42023475650
There are a variety of drugs for the treatment of polycystic ovary syndrome. Which drug or combination of drugs will have a positive effect on a woman's conception rate?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7630
- Evidence Id
- 16188
- Core Evidence Id
- 16188
- Source Meta Analysis Id
- 7624
- Herb2 Meta Analysis Id
- HBMA007624
- Crd Id
- CRD42023475650
- Title
- Effect of pharmacological intervention on pregnancy rates in women with polycystic ovary syndrome: a systematic review and meta-analysis.
- Review Question
- There are a variety of drugs for the treatment of polycystic ovary syndrome. Which drug or combination of drugs will have a positive effect on a woman's conception rate?
- Study Type Included
- Random Controlled Trials (RCTs)
- Condition Being Studied
- Polycystic ovary syndrome in women
- Participant
- Inclusion: Women diagnosed with polycystic ovary syndrome according to currently accepted criteria Exclusion:Men and healthy women and polycystic ovary syndrome patients under 18 years of age
- Animal
- Human Disease Modelled
- Intervention
- The medication interventions that will be investigated in this study include but are not limited to oral contraceptives, metformin, clomiphene citrate, letrozole, gonadotropins, and insulin-sensitizing agents. These interventions will be compared against a control group that did not receive any medication intervention but may have received lifestyle modifications or placebo treatment. The control group in this study will consist of PCOS patients who did not receive any medication intervention but may have been offered lifestyle modifications or placebo treatment in some studies. The control group will be used to compare the effect of medication intervention on the pregnancy rates in PCOS patients and to evaluate the efficacy of different medication interventions. The inclusion criteria for the control group will be consistent with those for the medication intervention group, ensuring appropriate comparability between the groups.
- Comparator Control
- Placebo. A group of hospital in-patients who were get PCOS.
- Main Outcome
- Hormones associated with female pregnancy and pregnancy success after prolonged observation Measures of effect relative risks, odds ratios, risk difference
- Outcome Measure
- Additional Outcome
- Weight changes, glucose tolerance levels, and hirsutism improved Measures of effect relative risks, odds ratios
- Study Method
- Individual patient data (IPD) meta-analysis, Intervention, Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- SUN YUANHONG [email protected]
- Organisational Affiliation
- Hengyang Medical School, University of South China https://www.usc.edu.cn/
- Funding Source
- Lei Xiaocan, Institute of Applied Anatomy and Reproductive Medicine, Hengyang Medical School, University of South China Grant number(s) State the funder, grant or award number and the date of award National Natural Science Foundation of China, 82101720, 2021
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-10-24
- Registration Date
- 2023-11-08
- Anticipated Start Date
- 2023-10-11
- Anticipated Completion Date
- 2024-07-04
- Title Cn
- 药物干预对多囊卵巢综合征女性妊娠率的影响:系统评价与Meta分析
- Title En
- Effect of pharmacological intervention on pregnancy rates in women with polycystic ovary syndrome: a systematic review and meta-analysis.
- Bilingual Status
- complete