Meta AnalysisID 7630

药物干预对多囊卵巢综合征女性妊娠率的影响:系统评价与Meta分析

CRD42023475650

There are a variety of drugs for the treatment of polycystic ovary syndrome. Which drug or combination of drugs will have a positive effect on a woman's conception rate?

Back to Browse

Relationship Network

Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...

Record Fields

Scalar fields from the final meta_analysis record.

Meta Analysis Id
7630
Evidence Id
16188
Core Evidence Id
16188
Source Meta Analysis Id
7624
Herb2 Meta Analysis Id
HBMA007624
Crd Id
CRD42023475650
Title
Effect of pharmacological intervention on pregnancy rates in women with polycystic ovary syndrome: a systematic review and meta-analysis.
Review Question
There are a variety of drugs for the treatment of polycystic ovary syndrome. Which drug or combination of drugs will have a positive effect on a woman's conception rate?
Study Type Included
Random Controlled Trials (RCTs)
Condition Being Studied
Polycystic ovary syndrome in women
Participant
Inclusion: Women diagnosed with polycystic ovary syndrome according to currently accepted criteria Exclusion:Men and healthy women and polycystic ovary syndrome patients under 18 years of age
Animal
Human Disease Modelled
Intervention
The medication interventions that will be investigated in this study include but are not limited to oral contraceptives, metformin, clomiphene citrate, letrozole, gonadotropins, and insulin-sensitizing agents. These interventions will be compared against a control group that did not receive any medication intervention but may have received lifestyle modifications or placebo treatment. The control group in this study will consist of PCOS patients who did not receive any medication intervention but may have been offered lifestyle modifications or placebo treatment in some studies. The control group will be used to compare the effect of medication intervention on the pregnancy rates in PCOS patients and to evaluate the efficacy of different medication interventions. The inclusion criteria for the control group will be consistent with those for the medication intervention group, ensuring appropriate comparability between the groups.
Comparator Control
Placebo. A group of hospital in-patients who were get PCOS.
Main Outcome
Hormones associated with female pregnancy and pregnancy success after prolonged observation Measures of effect relative risks, odds ratios, risk difference
Outcome Measure
Additional Outcome
Weight changes, glucose tolerance levels, and hirsutism improved Measures of effect relative risks, odds ratios
Study Method
Individual patient data (IPD) meta-analysis, Intervention, Meta-analysis, Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
SUN YUANHONG [email protected]
Organisational Affiliation
Hengyang Medical School, University of South China https://www.usc.edu.cn/
Funding Source
Lei Xiaocan, Institute of Applied Anatomy and Reproductive Medicine, Hengyang Medical School, University of South China Grant number(s) State the funder, grant or award number and the date of award National Natural Science Foundation of China, 82101720, 2021
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-10-24
Registration Date
2023-11-08
Anticipated Start Date
2023-10-11
Anticipated Completion Date
2024-07-04
Title Cn
药物干预对多囊卵巢综合征女性妊娠率的影响:系统评价与Meta分析
Title En
Effect of pharmacological intervention on pregnancy rates in women with polycystic ovary syndrome: a systematic review and meta-analysis.
Bilingual Status
complete