Meta AnalysisID 7479
耳鼻喉科阿片类药物处方：一项系统评价与Meta分析
CRD42023474614
The goal of this systematic review is to evaluate the amount of opioids prescribed and consumed following general otolaryngology procedures. The following questions will be addressed a. How much opioid is being prescribe
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Record Fields
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- Meta Analysis Id
- 7479
- Evidence Id
- 16037
- Core Evidence Id
- 16037
- Source Meta Analysis Id
- 7472
- Herb2 Meta Analysis Id
- HBMA007472
- Crd Id
- CRD42023474614
- Title
- Opioid Prescribing In Otolaryngology, a systematic review and meta-analysis
- Review Question
- The goal of this systematic review is to evaluate the amount of opioids prescribed and consumed following general otolaryngology procedures. The following questions will be addressed a. How much opioid is being prescribed after common otolaryngology procedures and how is this different depending on the type of surgery? b. How much opioid is being consumed after common otolaryngology procedures and how is this different depending on the type of surgery? c. Are there certain procedures where patients are left with more opioid then they use? d. How many patients are requesting refills after certain otolaryngology procedures?
- Study Type Included
- a. Study designs. We will include randomized controlled trials(RCTs), including cluster RCTs, controlled (non-randomized) clinical trials(CCTs) or cluster trials, prospective and retrospective comparative cohort studies, and case-control or nested case-control studies. We will exclude cross-sectional studies, case series, and case reports.
- Condition Being Studied
- Opioid prescribing and consumption in otolaryngology ambulatory proceedures
- Participant
- Participants. We will include adult patients over the age of 18 who previously underwent one of the following procedures: Oropharyngeal procedures including Tonsillectomy with or without adenoidectomy, uvulopalatopharyngoplasty; head and neck procedures including parotidectomy, thyroidectomy, parathyroidectomy, cervical lymph node excisions; nasal surgery including inferior turbinate reduction, septoplasty, rhinoplasty, and endoscopic sinus surgery; laryngology procedures including microlaryngoscopy; otologic procedures including stapedectomy, cochlear implantation, mastoidectomy, and tympanoplasty; facial trauma procedures including repair of mandible, midface, and nasal bone fractures. We will exclude children under the age of 18 and those patients having surgery for malignancy.
- Animal
- Human Disease Modelled
- Intervention
- Interventions. We will look at opioids prescribed and consumed in the patients. We will first determine what specific opioid the patient was prescribed. We will include common opioids prescribed after outpatient surgery including hydrocodone, oxycodone, tramadol, morphine, codeine, hydromorphone, fentanyl. These medications will be filtered to only including those prescribed in an oral form. We will use a standard conversion chart to calculate the morphine milligram equivalent of the specific opioid prescribed in order to get a standard amount of opioid for each patient. The conversion factor for different opioids is listed below according to the Center for Disease Control and Prevention 2022 Clinical Practice Guidelines.
- Comparator Control
- b. Participants. We will include adult patients over the age of 18 who previously underwent one of the following procedures: Oropharyngeal procedures including Tonsillectomy with or without adenoidectomy, uvulopalatopharyngoplasty; head and neck procedures including parotidectomy, thyroidectomy, parathyroidectomy, cervical lymph node excisions; nasal surgery including inferior turbinate reduction, septoplasty, rhinoplasty, and endoscopic sinus surgery; laryngology procedures including microlaryngoscopy; otologic procedures including stapedectomy, cochlear implantation, mastoidectomy, and tympanoplasty; facial trauma procedures including repair of mandible, midface, and nasal bone fractures. We will exclude children under the age of 18 and those patients having surgery for malignancy.
- Main Outcome
- 13- Primary Outcomes: The primary outcome will be the mean number of MME prescribed and consumed for patients undergoing various individual surgical procedures (ex. tonsillectomy, rhinoplasty, tympanoplasty) and grouped surgical procedures (ex. oropharyngeal, nasal, otologic).
- Outcome Measure
- Additional Outcome
- a. Secondary Outcomes: The Secondary outcomes for the study will include the number of refills a patient receives. Male prescribed and consumed MME vs. female prescribed and consumed MME. In addition what opioid was prescribed will also be included along with percent of patients who took other pain medications such as NSAIDs of acetaminophen. In addition, prescriber specialty and available demographics will be included as a secondary outcome as well.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Colten Wolf [email protected]
- Organisational Affiliation
- Loyola University Medicial Center
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- United States of America
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-10-20
- Registration Date
- 2023-10-31
- Anticipated Start Date
- 2023-10-30
- Anticipated Completion Date
- 2024-07-01
- Title Cn
- 耳鼻喉科阿片类药物处方：一项系统评价与Meta分析
- Title En
- Opioid Prescribing In Otolaryngology, a systematic review and meta-analysis
- Bilingual Status
- complete